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LOC100009136 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600390

Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are… More details

$815 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NP-5 (LOC100009136), Monoclonal Antibody
Full Product Name
NP-5 (Alpha Defensin 5, Defensin 5, DEF5, Defensin alpha 5, Defensin alpha 5 Paneth Cell-specific, Defensin alpha 5 Preproprotein, DEFA5, HD5, HD-5, HNP5, HNP-5, MGC129728)
Product Synonym Names
Anti -NP-5 (Alpha Defensin 5, Defensin 5, DEF5, Defensin alpha 5, Defensin alpha 5 Paneth Cell-specific, Defensin alpha 5 Preproprotein, DEFA5, HD5, HD-5, HNP5, HNP-5, MGC129728)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9A8
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris-glycine, 150mM sodium chloride, 0.05% sodium azide.
Purity/Purification
Purified
Purified
Specificity
Recognizes human HD5 at ~12kD. No crossreactivity is observed with HD6, lysozyme or sPLA2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
10,122 Da
3D Structure
ModBase 3D Structure for P07466
Immunogen
Full-length proHD5 protein [Swiss-Prot# Q01523]. The propeptide is the full-length protein. In the mature form it is cleaved at residue 63 (alanine). Cellular Localization: Secreted.
Applications Tested/Suitable for anti-LOC100009136 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-LOC100009136 antibody
Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (FFPE): 5-10ug/ml

Testing Data of anti-LOC100009136 antibody

Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using MBS600390.
Mouse Anti-LOC100009136 Monoclonal Antibody – Cat# MBS600390

Other Notes

Small volumes of anti-LOC100009136 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LOC100009136 purchase

MBS600390 is an antibody targeting LOC100009136. Also known as NP-5 (Alpha Defensin 5, Defensin 5, DEF5, Defensin alpha 5, Defensin alpha 5 Paneth Cell-specific, Defensin alpha 5 Preproprotein, DEFA5, HD5, HD-5, HNP5, HNP-5, MGC129728). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LOC100009136. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neutrophil antibiotic peptide NP-5
NCBI Official Symbol
LOC100009136
NCBI Official Synonym Symbols
CS-6; NP-5
UniProt Protein Name
Neutrophil antibiotic peptide NP-5
UniProt Synonym Protein Names
Microbicidal peptide NP-5
UniProt Entry Name
DEF6_RABIT
NCBI Protein Information
neutrophil antibiotic peptide NP-5; defensin np-5; corticostatin CS-6; microbicidal peptide NP-5

UniProt Comments for LOC100009136

Function: Microbicidal activity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the alpha-defensin family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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