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ARHGAP15 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004870

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARHGAP15, Polyclonal Antibody
Full Product Name
ARHGAP15 (Rho GTPase-activating Protein 15, ArhGAP15, Rho-type GTPase-activating Protein 15, BM-024, BM-030, BM-046)
Product Gene Name
Product Synonym Names
Anti -ARHGAP15 (Rho GTPase-activating Protein 15, ArhGAP15, Rho-type GTPase-activating Protein 15, BM-024, BM-030, BM-046)
Immunogen Sequence
MQKSTNSDTS VETLNSTRQG TGAVQMRIKN ANSHHDRLSQ SKSMILTDVG KVTEPISRHR RNHSQHILKD VIPPLEQLMV EKEGYLQKAK IADGGKKLRK NWSTSWIVLS SRRIEFYKES KQQALSNMKT GHKPESVDLC GAHIEWAKEK SSRKNVFQIT TVSGNEFLLQ SDIDFIILDW FHAIKNAIDR LPKDSSCPSR NLELFKIQRS SSTELLSHYD SDIKEQKPEH RKSLMFRLHH SASDTSDKNR VKSRLKKFIT RRPSLKTLQE KGLIKDQIFG SHLHKVCERE NSTVPWFVKQ CIEAVEKRGL DVDGIYRVSG NLATIQKLRF IVNQEEKLNL DDSQWEDIHV VTGALKMFFR ELPEPLFPYS FFEQFVEAIK KQDNNTRIEA VKSLVQKLPP PNRDTMKVLF GHLTKIVAKA SKNLMSTQSL GIVFGPTLLR AENETGNMAI HMVYQNQIAE LMLSEYSKIF GSEED
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ARHGAP15.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
54,544 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (143886899..144525921). Location: 2q22.2-q22.3
OMIM
610578
3D Structure
ModBase 3D Structure for Q53QZ3
Immunogen
Full length human ARHGAP15, aa1-475 (AAH38976.2).
Applications Tested/Suitable for anti-ARHGAP15 antibody
Western Blot (WB)
Application Notes for anti-ARHGAP15 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-ARHGAP15 antibody

Western Blot analysis of ARHGAP15 expression in transfected 293T cell line by ARHGAP15 polyclonal antibody. Lane 1: ARHGAP15 transfected lysate (52.25kD). Lane 2: Non-transfected lysate.
Mouse Anti-ARHGAP15 Polyclonal Antibody – Cat# MBS6004870

Other Notes

Small volumes of anti-ARHGAP15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGAP15 purchase

MBS6004870 is an antibody targeting ARHGAP15. Also known as ARHGAP15 (Rho GTPase-activating Protein 15, ArhGAP15, Rho-type GTPase-activating Protein 15, BM-024, BM-030, BM-046). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP15. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ARHGAP15
NCBI Official Synonym Full Names
Rho GTPase activating protein 15
NCBI Official Symbol
ARHGAP15
NCBI Official Synonym Symbols
BM046
UniProt Protein Name
Rho GTPase-activating protein 15
UniProt Synonym Protein Names
ArhGAP15; Rho-type GTPase-activating protein 15
UniProt Gene Name
ARHGAP15
UniProt Entry Name
RHG15_HUMAN
NCBI Protein Information
rho GTPase-activating protein 15; rho-type GTPase-activating protein 15

NCBI Summary for ARHGAP15

RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]

UniProt Comments for ARHGAP15

ARHGAP15: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 2q22.2-q22.3

Cellular Component: membrane; cytosol

Biological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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