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Glycophorin-B (GYPB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004892

MBS6004892 is an antibody targeting GYPB. Also known as Glycophorin-B, ID (GYPB, GPB,, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta, CD235b). Reactive in Human. Host: Rabbit. This protein is a minor sialoglycoprotein in erythrocyte membranes. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glycophorin-B (GYPB), Polyclonal Antibody
Full Product Name
Glycophorin-B, ID (GYPB, GPB,, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta, CD235b)
Product Gene Name
Product Synonym Names
Anti -Glycophorin-B, ID (GYPB, GPB,, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta, CD235b)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
9,782 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (144917257..144940498, complement). Location: 4q31.21
OMIM
111740
3D Structure
ModBase 3D Structure for P06028
Immunogen
GYPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the Central region of human GYPB.

Product Categories/Family for anti-GYPB antibody

Applications Tested/Suitable for anti-GYPB antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GYPB antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-GYPB antibody

Western Blot analysis of GYPB (arrow) using MBS6004892. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GYPB gene.
Rabbit Anti-GYPB Polyclonal Antibody – Cat# MBS6004892

Immunohistochemistry (IHC) of anti-GYPB antibody

Immunohistochemistry analysis of MBS6004892 in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Rabbit Anti-GYPB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6004892

Other Notes

Small volumes of anti-GYPB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GYPB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glycophorin-B
NCBI Official Synonym Full Names
glycophorin B (MNS blood group)
NCBI Official Symbol
GYPB
NCBI Official Synonym Symbols
SS; GPB; MNS; PAS-3; CD235b; GPB.NY; HGpMiX; GpMiIII; HGpMiVI; GYPHe.NY; HGpMiIII
UniProt Protein Name
Glycophorin-B
UniProt Synonym Protein Names
PAS-3; SS-active sialoglycoprotein; Sialoglycoprotein delta
Protein Family
UniProt Gene Name
GYPB
UniProt Synonym Gene Names
GPB
UniProt Entry Name
GLPB_HUMAN
NCBI Protein Information
glycophorin-B; Ss blood group; glycophorin MiX; glycophorin HeP2; glycophorin MiVI; glycophorin MiIII; sialoglycoprotein delta; SS-active sialoglycoprotein

NCBI Summary for GYPB

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]
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UniProt Comments for GYPB

GYPB: This protein is a minor sialoglycoprotein in erythrocyte membranes. Belongs to the glycophorin-A family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: integral to plasma membrane; plasma membrane

Disease: Malaria, Susceptibility To

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GYPB antibody

Organs/Tissues associated with anti-GYPB antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >26 publications with GYPB and Blood
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