Rabbit Anti-F11R Polyclonal Antibody – Cat# MBS6005100

JAM-A, Domain 1 (F11R) Antibody – Rabbit Polyclonal

Name: F11R Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6005100
Price: 1320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6005100

Junction adhesion molecule (JAM)-A (also known as JAM, JAM-1 or F11R). Together with JAM-C (JAM-2) and JAM-B (VE-JAM or JAM-3), JAM-A belongs to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAMs are important for a variety of… More details

$1320 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JAM-A, Domain 1 (F11r), Polyclonal Antibody

Full Product Name

JAM-A, Domain 1 (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, Platelet Adhesion Molecule 1, PAM-1, CD321, F11R, JAM1, JCAM, UNQ264/PRO301)

Product Gene Name

anti-F11r antibody

Product Synonym Names

Anti -JAM-A, Domain 1 (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, Platelet Adhesion Molecule 1, PAM-1, CD321, F11R, JAM1, JCAM, UNQ264/PRO301)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes the first extracellular domain of human JAM-A. Does not react with mouse JAM-A.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

32,370 Da

Chromosome Location

Chromosome: 13; NC_005112.3 (94453478..94477357). Location: 13q24

3D Structure

ModBase 3D Structure for Q9JHY1

Immunogen

Extracellular domain from full-length human JAM-A.

Product Categories/Family for anti-F11r antibody

Antibodies; Abs to Connexin; Junction Proteins

Applications Tested/Suitable for anti-F11r antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Application Notes for anti-F11r antibody

Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: Paraffin
Flow Cytometry: 1:50
Western Blot: 1:50

Other Notes

Small volumes of anti-F11r antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for F11r purchase

MBS6005100 is an antibody targeting F11r. Also known as JAM-A, Domain 1 (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, Platelet Adhesion Molecule 1, PAM-1, CD321, F11R, JAM1, JCAM, UNQ264/PRO301). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for F11r. It may not necessarily be applicable to this product.

NCBI GI #

16758636

NCBI GeneID

116479

NCBI Accession #

NP_446248.1

UniProt Primary Accession #

Q9JHY1

UniProt Related Accession #

Q9JHY1

GenBank Nucleotide #

NM_053796.1

NCBI Official Full Name

junctional adhesion molecule A

NCBI Official Synonym Full Names

F11 receptor

NCBI Official Symbol

F11r

NCBI Official Synonym Symbols

Jam1

UniProt Protein Name

Junctional adhesion molecule A

UniProt Synonym Protein Names

Junctional adhesion molecule 1

Protein Family

Junctional adhesion molecule

UniProt Gene Name

F11r

UniProt Synonym Gene Names

Jam1; JAM-A; JAM-1

UniProt Entry Name

JAM1_RAT

NCBI Protein Information

junctional adhesion molecule A; JAM-1; JAM-A; junctional adhesion molecule 1

UniProt Comments for F11r

JAM-A: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. Belongs to the immunoglobulin superfamily.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: microtubule cytoskeleton; tight junction; plasma membrane; integral to membrane; intercellular junction; cytoplasmic vesicle; cell junction

Molecular Function: protein binding; PDZ domain binding

Biological Process: response to radiation; viral reproduction; epithelial cell differentiation; actomyosin structure organization and biogenesis; cell adhesion; cell differentiation; positive regulation of blood pressure; intestinal absorption

Research Articles on F11r

1. Suggest a prognostic and possibly a pathogenic role of JAM-A in arterial hypertension.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-F11r antibody

Reference Product	PubMed Publications
Tjp1 antibody	>32 publications with F11r and Tjp1
Ocln antibody	>25 publications with F11r and Ocln
Jam3 antibody	>9 publications with F11r and Jam3
Itgb2 antibody	>3 publications with F11r and Itgb2
Cask antibody	>2 publications with F11r and Cask
Mllt4 antibody	>2 publications with F11r and Mllt4
Magi1 antibody	>1 publications with F11r and Magi1
Mpdz antibody	>1 publications with F11r and Mpdz

Pathways associated with anti-F11r antibody

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-cell Junction Organization Pathway antibodies	Cell-cell Junction Organization Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Integrin Cell Surface Interactions Pathway antibodies	Integrin Cell Surface Interactions Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram

Diseases associated with anti-F11r antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>30 publications with F11r and Inflammation
Necrosis Antibodies	>17 publications with F11r and Necrosis
Disease Models, Animal Antibodies	>14 publications with F11r and Disease Models, Animal
Breast Neoplasms Antibodies	>12 publications with F11r and Breast Neoplasms
Adenocarcinoma Antibodies	>7 publications with F11r and Adenocarcinoma
Neoplasm Metastasis Antibodies	>7 publications with F11r and Neoplasm Metastasis
Kidney Diseases Antibodies	>6 publications with F11r and Kidney Diseases
Neoplasm Invasiveness Antibodies	>5 publications with F11r and Neoplasm Invasiveness
Edema Antibodies	>5 publications with F11r and Edema
Brain Diseases Antibodies	>5 publications with F11r and Brain Diseases

Organs/Tissues associated with anti-F11r antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>13 publications with F11r and Lung
Kidney Antibodies	>12 publications with F11r and Kidney
Liver Antibodies	>12 publications with F11r and Liver
Embryonic Tissue Antibodies	>11 publications with F11r and Embryonic Tissue
Ovary Antibodies	>5 publications with F11r and Ovary
Prostate Antibodies	>1 publications with F11r and Prostate