Tetrahydrocannabinol, D9 Antibody – Mouse Monoclonal

Cannabinoids, a group of C21 compounds present in Cannabis sativa L., their carboxylic acids, analogs, and transformation products, are the active ingredients found in hasish and marihuana. (-)-trans-D9-tetrahydrocannabinol (D9-THC) is the major psychopharmacologically active component of cannabis. Cannabis affect cognition and memory, euphoria and sedation, and antinociception (analgesia) without the respiratory depression problems associated with opioid analgesics. D9-THC is also immunosuppressive and impairs cell-mediated immunity, humoral immunity and cellular defenses against a variety of infectious agents both in vivo and in vitro. To date, two sub-types of the G-protein coupled cannabinoid receptor, CB1 and CB2, have been identified. The first brain-derived endogenous cannabinoids, an unsaturated fatty-acid ethanolamide, arachidonylethanolamide (AEA, also called anandamide) was found in brain. AEA has higher affinity for the CB1 than for the CB2.

THC is rapidly adsorbed by the lungs and almost completely metabolized. The major metabolite is 11-nor-delta-9-tetrahydrocannbinol-9-carboxylic acid and is found with other metabolites in plasma, feces, and urine. THC-metabolites can be detected within hours or exposure and may be detectable for several days. A cut-off level of 50ng/ml marijuana metabolites has been selected as the initial screening level by the US Dept. of Health.

Small volumes of anti-Tetrahydrocannabinol, D9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS600536 is an antibody targeting Tetrahydrocannabinol, D9. Also known as Tetrahydrocannabinol, D9 (THC). Host: Mouse.