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IL15RA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6005668

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL15RA, Polyclonal Antibody
Full Product Name
IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha)
Product Gene Name
anti-IL15RA antibody
Product Synonym Names
Anti -IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
28,233 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (5994334..6020150, complement). Location: 10p15.1
OMIM
601070
3D Structure
ModBase 3D Structure for Q13261
Immunogen
IL15RA antibody is generated from rabbits immunized with a KLH conjugated synthetic between 78-106 amino acids selected from the Central region of human IL15RA.

Product Categories/Family for anti-IL15RA antibody

Antibodies; Abs to CD Markers
Applications Tested/Suitable for anti-IL15RA antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-IL15RA antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-IL15RA antibody

IL15RA Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL15RA antibody detected the IL15RA protein (arrow).
Rabbit Anti-IL15RA Polyclonal Antibody – Cat# MBS6005668

Other Notes

Small volumes of anti-IL15RA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL15RA purchase

MBS6005668 is an antibody targeting IL15RA. Also known as IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL15RA. It may not necessarily be applicable to this product.

NCBI GI #
377520151
NCBI GeneID
3601
NCBI Accession #
NP_001243694.1
UniProt Primary Accession #
Q13261
UniProt Secondary Accession #
Q5JVA1; Q5JVA2; Q5JVA4; Q6B0J2; Q7LDR4; Q7Z609; B4E2C2
UniProt Related Accession #
Q13261
GenBank Nucleotide #
NM_001256765.1
NCBI Official Full Name
interleukin-15 receptor subunit alpha isoform 4
NCBI Official Synonym Full Names
interleukin 15 receptor, alpha
NCBI Official Symbol
IL15RA
NCBI Official Synonym Symbols
CD215
UniProt Protein Name
Interleukin-15 receptor subunit alpha
Protein Family
Interleukin-15 receptor
UniProt Gene Name
IL15RA
UniProt Synonym Gene Names
IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA
UniProt Entry Name
I15RA_HUMAN
NCBI Protein Information
interleukin-15 receptor subunit alpha

UniProt Comments for IL15RA

IL15RA: High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves STAT3, STAT5, STAT6, JAK2 and SYK. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: Golgi membrane; extracellular space; endoplasmic reticulum membrane; nuclear membrane; cytoplasmic vesicle membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; signal transducer activity; protein binding

Biological Process: cell proliferation; cytokine and chemokine mediated signaling pathway; signal transduction
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Research Articles on IL15RA

1. Data show efficient production of noncovalently linked but stable heterodimer in clonal HEK293 cells and release of the processed IL-15.sIL-15Ralpha heterodimer in the medium.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL15RA antibody

 Reference Product  PubMed Publications
 IL15 antibody  >227 publications with IL15RA and IL15
 IL2RB antibody  >22 publications with IL15RA and IL2RB
 IL2RG antibody  >11 publications with IL15RA and IL2RG
 JAK3 antibody  >7 publications with IL15RA and JAK3
 JAK1 antibody  >6 publications with IL15RA and JAK1
 JAK2 antibody  >3 publications with IL15RA and JAK2

Pathways associated with anti-IL15RA antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram

Diseases associated with anti-IL15RA antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >25 publications with IL15RA and Necrosis
 Inflammation Antibodies  >20 publications with IL15RA and Inflammation
 Lymphoma Antibodies  >12 publications with IL15RA and Lymphoma
 Neoplasms, Experimental Antibodies  >5 publications with IL15RA and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >3 publications with IL15RA and Lung Neoplasms
 Nervous System Diseases Antibodies  >3 publications with IL15RA and Nervous System Diseases
 Prostatic Diseases Antibodies  >3 publications with IL15RA and Prostatic Diseases
 Hyperplasia Antibodies  >3 publications with IL15RA and Hyperplasia
 Hypertrophy Antibodies  >2 publications with IL15RA and Hypertrophy
 Liver Diseases Antibodies  >2 publications with IL15RA and Liver Diseases

Organs/Tissues associated with anti-IL15RA antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >164 publications with IL15RA and Blood
 Spleen Antibodies  >18 publications with IL15RA and Spleen
 Lung Antibodies  >13 publications with IL15RA and Lung
 Intestine Antibodies  >10 publications with IL15RA and Intestine
 Skin Antibodies  >8 publications with IL15RA and Skin
 Liver Antibodies  >6 publications with IL15RA and Liver
 Brain Antibodies  >5 publications with IL15RA and Brain
 Uterus Antibodies  >5 publications with IL15RA and Uterus
 Eye Antibodies  >3 publications with IL15RA and Eye
 Prostate Antibodies  >3 publications with IL15RA and Prostate
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