• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SPRR1B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6005771

SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SPRR1B, Polyclonal Antibody
Full Product Name
SPRR1B, CT (SPRR1B, Cornifin-B, 14.9kD pancornulin, Small proline-rich protein IB)
Product Gene Name
Product Synonym Names
Anti -SPRR1B, CT (SPRR1B, Cornifin-B, 14.9kD pancornulin, Small proline-rich protein IB)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
16,636 Da
3D Structure
ModBase 3D Structure for Q62267
Immunogen
SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60~89 amino acids from the C-terminal region of human SPRR1B.
Applications Tested/Suitable for anti-Sprr1b antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-Sprr1b antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100

Western Blot (WB) of anti-Sprr1b antibody

Western blot analysis of SPRR1B Antibody (C-term) in MDA-MB231, MDA-MB435 cell line lysates (35ug/lane). SPRR1B (arrow) was detected using the purified Pab.
Rabbit Anti-SPRR1B Polyclonal Antibody – Cat# MBS6005771

Immunohistochemistry (IHC) of anti-Sprr1b antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with SPRR1B Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-SPRR1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6005771

Other Notes

Small volumes of anti-Sprr1b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sprr1b purchase

MBS6005771 is an antibody targeting Sprr1b. Also known as SPRR1B, CT (SPRR1B, Cornifin-B, 14.9kD pancornulin, Small proline-rich protein IB). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Sprr1b. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
SPRR1b
UniProt Protein Name
Cornifin-B
UniProt Synonym Protein Names
Small proline-rich protein 1B
Protein Family
UniProt Gene Name
Sprr1b
UniProt Synonym Gene Names
SPR1 B; SPR1B
UniProt Entry Name
SPR1B_MOUSE

UniProt Comments for Sprr1b

SPRR3: Cross-linked envelope protein of keratinocytes. Belongs to the cornifin (SPRR) family.

Cellular Component: cytoplasm; cornified envelope

Molecular Function: structural constituent of cytoskeleton

Biological Process: regulation of cell shape; keratinization; peptide cross-linking

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000