Mouse Anti-ST3GAL1 Polyclonal Antibody – Cat# MBS6005785

Western Blot analysis of ST3GAL1 expression in transfected 293T cell line by ST3GAL1 polyclonal antibody. Lane 1: ST3GAL1 transfected lysate (37.4kD). Lane 2: Non-transfected lysate.

ST3GAL1 Antibody – Mouse Polyclonal

Name: ST3GAL1 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6005785
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6005785

It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ST3GAL1, Polyclonal Antibody

Full Product Name

ST3GAL1 (ST3O, Sialyltransferase 4A, SIAT4-A, SIAT4, SIAT4A, Alpha 2,3-ST 1, Beta-galactoside alpha-2,3-sialyltransferase 1, Gal-NAc6S, SIATFL, ST3Gal I, ST3GalI, ST3GalA.1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, DKFZp66

Product Gene Name

anti-St3gal1 antibody

Product Synonym Names

Anti -ST3GAL1 (ST3O, Sialyltransferase 4A, SIAT4-A, SIAT4, SIAT4A, Alpha 2,3-ST 1, Beta-galactoside alpha-2,3-sialyltransferase 1, Gal-NAc6S, SIATFL, ST3Gal I, ST3GalI, ST3GalA.1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, DKFZp66

Immunogen Sequence

MVTLRKRTLK VLTFLVLFIF LTSFFLNYSH TMVATTWFPK QMVLELSENL KRLIKHRPCT CTHCIGQRKL SAWFDERFNQ TMQPLLTAQN ALLEDDTYRW WLRLQREKKP NNLNDTIKEL FRVVPGNVDP MLEKRSVGCR RCAVVGNSGN LRESSYGPEI DSHDFVLRMN KAPTAGFEAD VGTKTTHHLV YPESFRELGD NVSMILVPFK TIDLEWVVSA ITTGTISHTY IPVPAKIRVK QDKILIYHPA FIKYVFDNWL QGHGRYPSTG ILSVIFSMHV CDEVDLYGFG ADSKGNWHHY WENNPSAGAF RKTGVHDADF ESNVTATLAS INKIRIFKGR

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human ST3GAL1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

39,073 Da

Chromosome Location

Chromosome: 15; NC_000081.6 (67102875..67176882, complement). Location: 15 D2; 15

3D Structure

ModBase 3D Structure for P54751

Immunogen

Full length human ST3GAL1, aa1-340 (NP_003024.1).

Product Categories/Family for anti-St3gal1 antibody

Antibodies; Abs to Enzymes

Applications Tested/Suitable for anti-St3gal1 antibody

Western Blot (WB)

Application Notes for anti-St3gal1 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-St3gal1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for St3gal1 purchase

MBS6005785 is an antibody targeting St3gal1. Also known as ST3GAL1 (ST3O, Sialyltransferase 4A, SIAT4-A, SIAT4, SIAT4A, Alpha 2,3-ST 1, Beta-galactoside alpha-2,3-sialyltransferase 1, Gal-NAc6S, SIATFL, ST3Gal I, ST3GalI, ST3GalA.1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, DKFZp66. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for St3gal1. It may not necessarily be applicable to this product.

NCBI GI #

71122198

NCBI GeneID

20442

NCBI Accession #

AAH99693.1

UniProt Primary Accession #

P54751

UniProt Secondary Accession #

Q11202

UniProt Related Accession #

P54751

NCBI Official Full Name

St3gal1 protein

NCBI Official Synonym Full Names

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

NCBI Official Symbol

St3gal1

NCBI Official Synonym Symbols

Siat4; Siat4a; ST3GalI; AI467004; St3gal-1; 5330418N22Rik

UniProt Protein Name

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

UniProt Synonym Protein Names

Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; ST3Gal I; ST3GalI; ST3GalA.1; ST3O; Sialyltransferase 4A

Protein Family

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase

UniProt Gene Name

St3gal1

UniProt Synonym Gene Names

Siat4; Siat4a; Alpha 2,3-ST 1; Beta-galactoside alpha-2,3-sialyltransferase 1; ST3GalI; SIAT4-A

UniProt Entry Name

SIA4A_MOUSE

NCBI Protein Information

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; ST3O; SIAT4-A; ST3Gal I; ST3GalA.1; gal-NAc6S; alpha 2,3-ST 1; ST3GAL-I sialyltransferase; Gal beta1,3 GalNAc alpha2,3 sialyltransferase; beta-galactoside alpha-2,3-sialyltransferase 1; gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase

UniProt Comments for St3gal1

ST3GAL1: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 29 family.

Protein type: EC 2.4.99.4; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Transferase; Glycan Metabolism - keratan sulfate biosynthesis; Glycan Metabolism - O-glycan biosynthesis

Cellular Component: Golgi apparatus; membrane; integral to membrane; extracellular region; integral to Golgi membrane

Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; sialyltransferase activity; beta-galactoside alpha-2,3-sialyltransferase activity

Biological Process: protein amino acid glycosylation; protein amino acid phosphorylation

Research Articles on St3gal1

1. tryptophan and cysteine residues conserved in ST3Gal I are critical for its activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-St3gal1 antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies	Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies	Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies	Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies	Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
Keratan Sulfate Biosynthesis Pathway antibodies	Keratan Sulfate Biosynthesis Pathway Diagram
Keratan Sulfate/keratin Metabolism Pathway antibodies	Keratan Sulfate/keratin Metabolism Pathway Diagram

Diseases associated with anti-St3gal1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with St3gal1 and Inflammation
Neoplasms Antibodies	>1 publications with St3gal1 and Neoplasms
Necrosis Antibodies	>1 publications with St3gal1 and Necrosis

Organs/Tissues associated with anti-St3gal1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with St3gal1 and Brain