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CCNL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6006167

CCNL2 is a transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CCNL2, Polyclonal Antibody
Full Product Name
CCNL2, ID (CCNL2, Cyclin-L2, Paneth cell-enhanced expression protein)
Product Gene Name
Product Synonym Names
Anti -CCNL2, ID (CCNL2, Cyclin-L2, Paneth cell-enhanced expression protein)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
58,147 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (1321091..1334718, complement). Location: 1p36.33
OMIM
613482
3D Structure
ModBase 3D Structure for Q96S94
Immunogen
CCNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the Central region of human CCNL2.

Product Categories/Family for anti-CCNL2 antibody

Applications Tested/Suitable for anti-CCNL2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CCNL2 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-CCNL2 antibody

CCNL2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CCNL2 antibody detected the CCNL2 protein (arrow).
Rabbit Anti-CCNL2 Polyclonal Antibody – Cat# MBS6006167

Other Notes

Small volumes of anti-CCNL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCNL2 purchase

MBS6006167 is an antibody targeting CCNL2. Also known as CCNL2, ID (CCNL2, Cyclin-L2, Paneth cell-enhanced expression protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCNL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CCNL2 protein
NCBI Official Synonym Full Names
cyclin L2
NCBI Official Symbol
CCNL2
NCBI Official Synonym Symbols
CCNM; PCEE; SB138; ANIA-6B; HLA-ISO; HCLA-ISO
UniProt Protein Name
Cyclin-L2
UniProt Synonym Protein Names
Paneth cell-enhanced expression protein
Protein Family
UniProt Gene Name
CCNL2
UniProt Entry Name
CCNL2_HUMAN
NCBI Protein Information
cyclin-L2; cyclin M; paneth cell-enhanced expression protein

NCBI Summary for CCNL2

The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for CCNL2

CCNL2: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis. Belongs to the cyclin family. Cyclin L subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Transcription regulation

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleolus; nuclear speck; cell junction; nucleus

Molecular Function: protein kinase binding

Biological Process: RNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of cyclin-dependent protein kinase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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