Rabbit Anti-SHISA5 Polyclonal Antibody – Cat# MBS6006263

SHISA5 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SHISA5 antibody detected the SHISA5 protein (arrow).

SHISA5 Antibody – Rabbit Polyclonal

Name: SHISA5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6006263
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6006263

SHISA5 can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SHISA5, Polyclonal Antibody

Full Product Name

SHISA5, ID (SHISA5, SCOTIN, Protein shisa-5, Putative NF-kappa-B-activating protein 120, Scotin)

Product Gene Name

anti-SHISA5 antibody

Product Synonym Names

Anti -SHISA5, ID (SHISA5, SCOTIN, Protein shisa-5, Putative NF-kappa-B-activating protein 120, Scotin)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

25,582 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (48509197..48542259, complement). Location: 3p21.31

OMIM

607290

3D Structure

ModBase 3D Structure for Q8N114

Immunogen

SHISA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the Central region of human SHISA5.

Product Categories/Family for anti-SHISA5 antibody

Antibodies; Abs to Apoptosis

Applications Tested/Suitable for anti-SHISA5 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-SHISA5 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-SHISA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SHISA5 purchase

MBS6006263 is an antibody targeting SHISA5. Also known as SHISA5, ID (SHISA5, SCOTIN, Protein shisa-5, Putative NF-kappa-B-activating protein 120, Scotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SHISA5. It may not necessarily be applicable to this product.

NCBI GI #

33876247

NCBI GeneID

51246

NCBI Accession #

AAH01463.2

UniProt Primary Accession #

Q8N114

UniProt Secondary Accession #

Q69YY9; Q7Z433; Q8NHL9; Q96MW8; Q9BV58; B3KW99

UniProt Related Accession #

Q8N114

NCBI Official Full Name

SHISA5 protein

NCBI Official Synonym Full Names

shisa family member 5

NCBI Official Symbol

SHISA5

NCBI Official Synonym Symbols

SCOTIN

UniProt Protein Name

Protein shisa-5

UniProt Synonym Protein Names

Putative NF-kappa-B-activating protein 120; Scotin

Protein Family

Protein shisa

UniProt Gene Name

SHISA5

UniProt Synonym Gene Names

SCOTIN

UniProt Entry Name

SHSA5_HUMAN

NCBI Protein Information

protein shisa-5; shisa homolog 5; putative NF-kappa-B-activating protein 120

NCBI Summary for SHISA5

This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

UniProt Comments for SHISA5

SCOTIN: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. Belongs to the shisa family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; integral to membrane

Molecular Function: signal transducer activity; protein binding; WW domain binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

Research Articles on SHISA5

1. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SHISA5 antibody

Reference Product	PubMed Publications
TP53 antibody	>2 publications with SHISA5 and TP53

Pathways associated with anti-SHISA5 antibody

Products by Pathway	Pathway Diagram
P53 Signaling Pathway antibodies	P53 Signaling Pathway Diagram
P53 Signaling Pathway antibodies	P53 Signaling Pathway Diagram

Diseases associated with anti-SHISA5 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with SHISA5 and Neoplasms