Mouse Anti-TAF1C Polyclonal Antibody – Cat# MBS6006403

Western Blot analysis of TAF1C expression in transfected 293T cell line by TAF1C polyclonal antibody. Lane 1: TAF1C transfected lysate (85.25kD). Lane 2: Non-transfected lysate.

TAF1C Antibody – Mouse Polyclonal

Name: TAF1C Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6006403
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6006403

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAF1C, Polyclonal Antibody

Full Product Name

TAF1C (TATA Box-binding Protein-associated Factor RNA Polymerase I Subunit C, RNA Polymerase I-specific TBP-associated Factor 110 kDa, TAFI110, TATA Box-binding Protein-associated Factor 1C, TBP-associated Factor 1C, Transcription Initiation Factor SL1/TI

Product Gene Name

anti-TAF1C antibody

Product Synonym Names

Anti -TAF1C (TATA Box-binding Protein-associated Factor RNA Polymerase I Subunit C, RNA Polymerase I-specific TBP-associated Factor 110 kDa, TAFI110, TATA Box-binding Protein-associated Factor 1C, TBP-associated Factor 1C, Transcription Initiation Factor SL1/TI

Immunogen Sequence

MLPPLIDPWD PGLTARDLLF RGGYRYRKRP RVVLDVTEQI SRFLLDHGDV AFAPLGKLML ENFKLEGAGS RTKKKTVVSV KKLLQDLGGH QPWGCPWAYL SNRQRRFSIL GGPILGTSVA SHLAELLHEE LVLRWEQLLL DEACTGGALA WVPGRTPQFG QLVYPAGGAQ DRLHFQEVVL TPGDNPQFLG KPGRIQLQGP VRQVVTCTVQ GETLLAVRSD YHCAVWKFGK QWQPTLLQAM QVEKGATGIS LSPHLPGELA ICSRSGAVCL WSPEDGLRQI YRDPETLVFR DSSSWRWADF TAHPRVLTVG DRTGVKMLDT QGPPGCGLLL FRLGAEASCQ KGERVLLTQY LGHSSPKCLP PTLHLVCTQF SLYLVDERLP LVPMLKWNHG LPSPLLLARL LPPPRPSCVQ PLLLGGQGGQ LQLLHLAEGA SVPRLAGPPQ SLPSRIDSLP AFPLLEPKIQ WRLQERLKAP TIGLAAVVPP MPSAPTPGLV LFQLSAAGDV FYQQLRPQVD SSLRRDAGPP GDTQPDCHAP TASWTSQDTA GCSQWLKALL KVPLAPPVWT APTFTHRQML GSTELRREEE EGQRLGVLRK AMARGQLLLQ RDLGSLPAAE PPPAPESGLE DKLSERLGEA WAGRGAAWWE RQQGRTSEPG RQTRRPKRRT QLSSSFSLSG HVDPSEDTSS PHSPEWPPAD ALPLPPTTPP SQELTPDACA QGVPSEQRQM LRDYMAKLPP QRDTPGCATT PPHSQASSVR ATRSQQHTPV LSSSQPLRKK PRMGF

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human TAF1C.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

95,213 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (84211453..84220676, complement). Location: 16q24

OMIM

604905

3D Structure

ModBase 3D Structure for Q15572

Immunogen

Full length human TAF1C, aa1-775 (AAH28131.1).

Product Categories/Family for anti-TAF1C antibody

Antibodies; Abs to Enzymes; Polymerase

Applications Tested/Suitable for anti-TAF1C antibody

Western Blot (WB)

Application Notes for anti-TAF1C antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-TAF1C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAF1C purchase

MBS6006403 is an antibody targeting TAF1C. Also known as TAF1C (TATA Box-binding Protein-associated Factor RNA Polymerase I Subunit C, RNA Polymerase I-specific TBP-associated Factor 110 kDa, TAFI110, TATA Box-binding Protein-associated Factor 1C, TBP-associated Factor 1C, Transcription Initiation Factor SL1/TI. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TAF1C. It may not necessarily be applicable to this product.

NCBI GI #

341926287

NCBI GeneID

9013

NCBI Accession #

NP_001230088.1

UniProt Primary Accession #

Q15572

UniProt Secondary Accession #

Q59F67; Q8N6V3; B7Z5K5; B7Z5S4; B7Z908; B7Z9L7

UniProt Related Accession #

Q15572

GenBank Nucleotide #

NM_001243159.1

NCBI Official Full Name

TATA box-binding protein-associated factor RNA polymerase I subunit C isoform 5

NCBI Official Synonym Full Names

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa

NCBI Official Symbol

TAF1C

NCBI Official Synonym Symbols

SL1; TAFI95; TAFI110; MGC:39976

UniProt Protein Name

TATA box-binding protein-associated factor RNA polymerase I subunit C

UniProt Synonym Protein Names

RNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit C

Protein Family

TATA box-binding protein-associated factor

UniProt Gene Name

TAF1C

UniProt Synonym Gene Names

TAFI110

UniProt Entry Name

TAF1C_HUMAN

NCBI Protein Information

TATA box-binding protein-associated factor RNA polymerase I subunit C; SL1, 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box-binding protein-associated factor 1C; transcription initiation factor SL1/TIF-IB subunit C; RNA polymerase I-specific TBP-associated factor 110 kDa

NCBI Summary for TAF1C

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]

UniProt Comments for TAF1C

TAF1C: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: nucleoplasm

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase II promoter; chromatin silencing at rDNA; negative regulation of gene expression, epigenetic; transcription from RNA polymerase I promoter; RNA elongation from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic

Research Articles on TAF1C

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAF1C antibody

Reference Product	PubMed Publications
TBP antibody	>9 publications with TAF1C and TBP
TAF1A antibody	>5 publications with TAF1C and TAF1A
TAF1B antibody	>5 publications with TAF1C and TAF1B

Pathways associated with anti-TAF1C antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RNA Polymerase I Chain Elongation Pathway antibodies	RNA Polymerase I Chain Elongation Pathway Diagram
RNA Polymerase I Promoter Clearance Pathway antibodies	RNA Polymerase I Promoter Clearance Pathway Diagram
RNA Polymerase I Promoter Escape Pathway antibodies	RNA Polymerase I Promoter Escape Pathway Diagram
RNA Polymerase I Transcription Pathway antibodies	RNA Polymerase I Transcription Pathway Diagram
RNA Polymerase I Transcription Initiation Pathway antibodies	RNA Polymerase I Transcription Initiation Pathway Diagram
RNA Polymerase I Transcription Termination Pathway antibodies	RNA Polymerase I Transcription Termination Pathway Diagram
RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies	RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram

Diseases associated with anti-TAF1C antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with TAF1C and Neoplasms
Hypertrophy Antibodies	>1 publications with TAF1C and Hypertrophy
Cell Transformation, Neoplastic Antibodies	>1 publications with TAF1C and Cell Transformation, Neoplastic
Autistic Disorder Antibodies	>1 publications with TAF1C and Autistic Disorder

Organs/Tissues associated with anti-TAF1C antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with TAF1C and Blood
Thyroid Antibodies	>1 publications with TAF1C and Thyroid