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GOSR1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600659

GS28, also known as p28 or GOS28, is a 28kD integral membrane protein on the surface of the Golgi apparatus that serves as a t-SNARE in ER to Golgi transport (2). The N-terminal of GS28/GOS28 is exposed to the cytosol and is anchored to the cis Golgi via a 20… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GS28 (GOSR1), Monoclonal Antibody
Full Product Name
GS28 (GOS28, p28)
Product Gene Name
Product Synonym Names
Anti -GS28 (GOS28, p28)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E99
Host
Mouse
Species Reactivity
Bovine, Canine, Chicken, Hamster, Mouse, Porcine, Rabbit, Rat, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes rat GS28 at~28kD. Recognized as a Cis Golgi marker, exposed to the cytosol, as determined by indirect immunofluoresence microscopy. Species Crossreactivity: mouse, hamster, rabbit, bovine, sheep, porcine, canine and chicken.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
28,613 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (28804426..28853832). Location: 17q11
OMIM
604026
3D Structure
ModBase 3D Structure for O95249
Immunogen
Rat liver Golgi-enriched membranes.
Positive Control
Rat Brain Tissue Extract

Product Categories/Family for anti-GOSR1 antibody

Applications Tested/Suitable for anti-GOSR1 antibody
Western Blot (WB)
Application Notes for anti-GOSR1 antibody
Suitable for use in Western Blot.
Dilution: Western Blot (ECL): 1:1000

Western Blot (WB) of anti-GOSR1 antibody

Western blot analysis of porcine kidney ESK-4 cell lysate, probed with MBS600659.
Mouse Anti-GOSR1 Monoclonal Antibody – Cat# MBS600659

Other Notes

Small volumes of anti-GOSR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GOSR1 purchase

MBS600659 is an antibody targeting GOSR1. Also known as GS28 (GOS28, p28). Reactive in Bovine, Canine, Chicken, Hamster, Mouse, Porcine, Rabbit, Rat, Sheep. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GOSR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Golgi SNAP receptor complex member 1 isoform 2
NCBI Official Synonym Full Names
golgi SNAP receptor complex member 1
NCBI Official Symbol
GOSR1
NCBI Official Synonym Symbols
P28; GS28; GOS28; GOLIM2; GOS-28; GOS28/P28
UniProt Protein Name
Golgi SNAP receptor complex member 1
UniProt Synonym Protein Names
28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28
UniProt Gene Name
GOSR1
UniProt Synonym Gene Names
GS28; GOS-28
UniProt Entry Name
GOSR1_HUMAN
NCBI Protein Information
Golgi SNAP receptor complex member 1; cis-golgi SNARE; Golgi SNARE 28 kDa; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; golgi integral membrane protein 2

NCBI Summary for GOSR1

This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GOSR1

GOSR1: a single-pass type IV Golgi membrane protein. Enriched on vesicular components at the terminal rims of the Golgi. Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR2, STX5, GABARAPL2 and YKT6.

Protein type: Vesicle; Autophagy; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q11

Cellular Component: SNARE complex; Golgi membrane; Golgi apparatus; cis-Golgi network; membrane; integral to membrane

Molecular Function: SNAP receptor activity

Biological Process: intra-Golgi vesicle-mediated transport; protein transport; ER to Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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