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ISL2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600690

MBS600690 is an antibody targeting ISL2. Also known as ISL2 (Insulin Gene Enhancer Protein ISL-2 (Islet-2), ISL LIM Homeobox 2). Reactive in Human. Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ISL2, Monoclonal Antibody
Full Product Name
ISL2 (Insulin Gene Enhancer Protein ISL-2 (Islet-2), ISL LIM Homeobox 2)
Product Gene Name
Product Synonym Names
Anti -ISL2 (Insulin Gene Enhancer Protein ISL-2 (Islet-2), ISL LIM Homeobox 2)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
8J122
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 1% BSA and 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human ISL2.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
39,768 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (76629147..76634816). Location: 15q23
OMIM
609481
3D Structure
ModBase 3D Structure for Q96A47
Immunogen
Partial sequence of recombinant full-length protein to human ISL2
Applications Tested/Suitable for anti-ISL2 antibody
Western Blot (WB), Gel Shift Assay (GS/EMSA)
Application Notes for anti-ISL2 antibody
Suitable for use in Dot Blot and Western Blot.

Testing Data of anti-ISL2 antibody

Mouse Anti-ISL2 Monoclonal Antibody – Cat# MBS600690

Other Notes

Small volumes of anti-ISL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ISL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
insulin gene enhancer protein ISL-2
NCBI Official Synonym Full Names
ISL LIM homeobox 2
NCBI Official Symbol
ISL2
NCBI Official Synonym Symbols
FLJ10160
UniProt Protein Name
Insulin gene enhancer protein ISL-2
UniProt Gene Name
ISL2
UniProt Entry Name
ISL2_HUMAN
NCBI Protein Information
insulin gene enhancer protein ISL-2; islet-2; OTTHUMP00000184891; ISL2 transcription factor, LIM/homeodomain, (islet-2)

UniProt Comments for ISL2

islet-2: Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding; sequence-specific DNA binding

Biological Process: peripheral nervous system neuron development; negative regulation of neuron differentiation; visceral motor neuron differentiation; regulation of transcription, DNA-dependent; spinal cord motor neuron cell fate specification; neuron development; retinal ganglion cell axon guidance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ISL2 antibody

Diseases associated with anti-ISL2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with ISL2 and Inflammation
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