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HAPLN4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600721

Hyaluronan and Proteoglycan Link Protein 4, (HAPLN4), also known as brain link protein 2, is one of four secreted HAPLN family proteoglycans that bind hyaluronan. HAPLN4 contains one Ig-type C2-set domain and two link domains. It is predominantly expressed in… More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HAPLN4, Monoclonal Antibody
Full Product Name
HAPLN4 (Hyaluronan and Proteoglycan Link Protein 4, Brain Link Protein 2)
Product Gene Name
Product Synonym Names
Anti -HAPLN4 (Hyaluronan and Proteoglycan Link Protein 4, Brain Link Protein 2)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
7H33
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS, 40-50% glycerol. If 0.2ml is used, the concentration will be 0.5mg/ml.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human HAPLN4. Does not react with recombinant human HAPLN1.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, PBS. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
42,801 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (19366450..19373596, complement). Location: 19p13.1
3D Structure
ModBase 3D Structure for Q86UW8
Immunogen
NS0-derived recombinant human HAPLN4.
Hybridoma
The fusion of mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human HAPLN4.
Applications Tested/Suitable for anti-HAPLN4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-HAPLN4 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Direct ELISA: 0.5-1ug/ml The detection limit is ~5ng/well.
Western Blot: 1-2ug/ml Using a colorimetric detection system, the detection kimit is ~1ng/lane and ~25ng/lane under non-reducing and reducing conditions respectively. Chemilunescent detection will increase sensitivity by 5-50 fold.

Other Notes

Small volumes of anti-HAPLN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAPLN4 purchase

MBS600721 is an antibody targeting HAPLN4. Also known as HAPLN4 (Hyaluronan and Proteoglycan Link Protein 4, Brain Link Protein 2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HAPLN4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hyaluronan and proteoglycan link protein 4
NCBI Official Synonym Full Names
hyaluronan and proteoglycan link protein 4
NCBI Official Symbol
HAPLN4
NCBI Official Synonym Symbols
BRAL2; KIAA1926
UniProt Protein Name
Hyaluronan and proteoglycan link protein 4
UniProt Synonym Protein Names
Brain link protein 2
UniProt Gene Name
HAPLN4
UniProt Synonym Gene Names
BRAL2; KIAA1926
UniProt Entry Name
HPLN4_HUMAN
NCBI Protein Information
hyaluronan and proteoglycan link protein 4; brain link protein 2

UniProt Comments for HAPLN4

HAPLN4: Binds to hyaluronic acid and may be involved in formation of the extracellular matrix. Belongs to the HAPLN family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: proteinaceous extracellular matrix

Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding

Biological Process: central nervous system development; cell adhesion; skeletal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-HAPLN4 antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with HAPLN4 and Atrophy

Organs/Tissues associated with anti-HAPLN4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with HAPLN4 and Brain
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