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General Transcription Factor IIE, Polypeptide 2beta, 34kD (GTF2E2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600737

MBS600737 is an antibody targeting GTF2E2. Also known as General Transcription Factor IIE, Polypeptide 2beta, 34kD (GTF2E2, TF2E2, TFIIE-B). Reactive in Human, Mouse, Rat. Host: Mouse. More details

$685 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
General Transcription Factor IIE, Polypeptide 2beta, 34kD (GTF2E2), Monoclonal Antibody
Full Product Name
General Transcription Factor IIE, Polypeptide 2beta, 34kD (GTF2E2, TF2E2, TFIIE-B)
Product Gene Name
anti-GTF2E2 antibody
Product Synonym Names
Anti -General Transcription Factor IIE, Polypeptide 2beta, 34kD (GTF2E2, TF2E2, TFIIE-B)
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
8C160
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human General Transcription Factor IIE, Polypeptide 2beta, 34kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
33,044 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (30436031..30515738, complement). Location: 8p12
OMIM
189964
3D Structure
ModBase 3D Structure for P29084
Immunogen
Partial sequence of recombinant full-length protein to human General Transcription Factor IIE, Polypeptide 2beta, 34kD

Product Categories/Family for anti-GTF2E2 antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-GTF2E2 antibody
Western Blot (WB)
Application Notes for anti-GTF2E2 antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

Testing Data of anti-GTF2E2 antibody

Mouse Anti-GTF2E2 Monoclonal Antibody – Cat# MBS600737

Western Blot (WB) of anti-GTF2E2 antibody

Detection of GTF2E2 by Western blot. Samples: Whole cell lysate from human HEK293 (H, 25 μg) , mouse NIH3T3 (M, 25 μg) and rat F2408 (R, 25 μg) cells. Predicted molecular weight: 33 kD
Mouse Anti-GTF2E2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS600737

Immunostaining (IS) of anti-GTF2E2 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with MBS600737 mAb.
Mouse Anti-GTF2E2 Monoclonal Antibody, Immunostaining (IS) – Cat# MBS600737

Other Notes

Small volumes of anti-GTF2E2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2E2. It may not necessarily be applicable to this product.

NCBI GI #
119583852
NCBI GeneID
2961
UniProt Primary Accession #
P29084
UniProt Secondary Accession #
Q9H2B9; D3DSV2
UniProt Related Accession #
P29084
NCBI Official Full Name
general transcription factor IIE, polypeptide 2, beta 34kDa, isoform CRA_c
NCBI Official Synonym Full Names
general transcription factor IIE, polypeptide 2, beta 34kDa
NCBI Official Symbol
GTF2E2
NCBI Official Synonym Symbols
FE; TF2E2; TFIIE-B
UniProt Protein Name
Transcription initiation factor IIE subunit beta
UniProt Synonym Protein Names
General transcription factor IIE subunit 2
Protein Family
General transcription factor
UniProt Gene Name
GTF2E2
UniProt Synonym Gene Names
TF2E2
UniProt Entry Name
T2EB_HUMAN
NCBI Protein Information
transcription initiation factor IIE subunit beta; TFIIE-beta; OTTHUMP00000225416; general transcription factor IIE subunit 2

UniProt Comments for GTF2E2

GTF2E2: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. Belongs to the TFIIE beta subunit family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: nucleoplasm; cytoplasm; transcription factor TFIIE complex; nucleus

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; viral reproduction; RNA elongation from RNA polymerase II promoter; gene expression
Show more

Research Articles on GTF2E2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GTF2E2 antibody

 Reference Product  PubMed Publications
 GTF2E1 antibody  >1 publications with GTF2E2 and GTF2E1

Pathways associated with anti-GTF2E2 antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Eukaryotic Transcription Initiation Pathway antibodies  Eukaryotic Transcription Initiation Pathway Diagram
 Formation And Maturation Of MRNA Transcript Pathway antibodies  Formation And Maturation Of MRNA Transcript Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 HIV-1 Transcription Initiation Pathway antibodies  HIV-1 Transcription Initiation Pathway Diagram
 Late Phase Of HIV Life Cycle Pathway antibodies  Late Phase Of HIV Life Cycle Pathway Diagram
 RNA Polymerase II HIV-1 Promoter Escape Pathway antibodies  RNA Polymerase II HIV-1 Promoter Escape Pathway Diagram

Diseases associated with anti-GTF2E2 antibody

 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >2 publications with GTF2E2 and Metabolic Diseases
 Breast Neoplasms Antibodies  >1 publications with GTF2E2 and Breast Neoplasms
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