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CD68CD68 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600751

Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell… More details

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Product Overview

Online Datasheet in PDF
Product Name
CD68CD68, Monoclonal Antibody
Full Product Name
Anti - CD68CD68 (MACROSIALIN, DKFZp686M18236, Macrophage antigen, SCARD1, Scavenger receptor class D member1) (FITC)
Product Synonym Names
CD68CD68 (MACROSIALIN, DKFZp686M18236, Macrophage antigen, SCARD1, Scavenger receptor class D member1) (FITC)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6A323
Host
Host: Mouse
Source: Human
Species Reactivity
Human
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 1% sodium azide.
Purity/Purification
Purified by Protein A affinity chromatography.
Specificity
Recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukaemia studies.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Cell suspensions of human lymph node.

Product Categories/Family for anti-CD68CD68 antibody

Applications Tested/Suitable for anti-CD68CD68 antibody
Flow Cytometry
Application Notes for anti-CD68CD68 antibody
Suitable for use in Flow Cytometry. Other applications not tested.
Dilution: Flow Cytometry: Use 10ul to label 10e6 cells in 100ul. Membrane permeabilization is required for this application.
Optimal dilution determined by the researcher

Product References and Citations for anti-CD68CD68 antibody

• 1. Kreipe, H. et al. (1987). Ki-M7 Monoclonal Antibody Specific for Myelomonocytic Cell Lineage and Macrophages in Human. J. Histochem. Cytochem. 35(10): 1117-1126.
• 2. Diop, O.M. et al. (2000). High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys. J. Virology 74(16): 7538-7547.
• 3. Micklem, K. et al. (1989). A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies. Brit. J. Haem 73: 6-11.
• 4. Glushakova, S.et al. (1999). Nef Enhances Human Immunodeficiency Virus Replication and Responsiveness to Interleukin-2 in Human Lymphoid Tissue Ex Vivo. J. Virology 73(5): 3968-3974.
• 5. Sadovnikova, E. et al. (2002). The CD68 protein as a potential target for leukaemia-reactive CTL. Leukemia 16(10): 2019-2026.

Other Notes

Small volumes of anti-CD68CD68 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD68CD68 purchase

MBS600751 is an antibody targeting CD68CD68. Also known as Anti - CD68CD68 (MACROSIALIN, DKFZp686M18236, Macrophage antigen, SCARD1, Scavenger receptor class D member1) (FITC). Reactive in Human. Host: Mouse
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CD68CD68. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Official Full Name
CD68 antigen

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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