1, Multiple Clones (MART) Antibody – Mouse Monoclonal

MELAN-A/MART-1 is a melanocyte differentiation marker. MELAN-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. MELAN-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Seven other melanoma-associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-1, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

Small volumes of anti-MART-1, multiple clones antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS600777 is an antibody targeting MART-1, multiple clones. Also known as MART-1, multiple clones (+2) (Melanoma Antigen Recognized by T-cells 1, Melan-A) (BSA & Azide Free). Reactive in Equine, Human. Host: Mouse.