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MTA3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6007974

MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTA3, Polyclonal Antibody
Full Product Name
MTA3, CT (MTA3, KIAA1266, Metastasis-associated protein MTA3)
Product Gene Name
Product Synonym Names
Anti -MTA3, CT (MTA3, KIAA1266, Metastasis-associated protein MTA3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
67,504 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (42721709..43011080). Location: 2p21
OMIM
609050
3D Structure
ModBase 3D Structure for Q9BTC8
Immunogen
MTA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from the C-terminal region of human MTA3.

Product Categories/Family for anti-MTA3 antibody

Applications Tested/Suitable for anti-MTA3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MTA3 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-MTA3 antibody

MTA3 Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the MTA3 antibody detected the MTA3 protein (arrow).
Rabbit Anti-MTA3 Polyclonal Antibody – Cat# MBS6007974

Other Notes

Small volumes of anti-MTA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTA3 purchase

MBS6007974 is an antibody targeting MTA3. Also known as MTA3, CT (MTA3, KIAA1266, Metastasis-associated protein MTA3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MTA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metastasis-associated protein MTA3 isoform a
NCBI Official Synonym Full Names
metastasis associated 1 family, member 3
NCBI Official Symbol
MTA3
UniProt Protein Name
Metastasis-associated protein MTA3
UniProt Gene Name
MTA3
UniProt Synonym Gene Names
KIAA1266
UniProt Entry Name
MTA3_HUMAN
NCBI Protein Information
metastasis-associated protein MTA3; metastasis associated family, member 3; metastasis associated gene family, member 3

UniProt Comments for MTA3

MTA3: Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleus

Molecular Function: protein binding; zinc ion binding; sequence-specific DNA binding; chromatin binding; transcription factor activity

Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MTA3 antibody

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