Mouse Anti-LMAN2 Monoclonal Antibody – Cat# MBS600830

Lectin, Mannose-Binding 2 (LMAN2) Antibody – Mouse Monoclonal

Name: LMAN2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS600830
Price: 850 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600830

Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high… More details

$850 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lectin, Mannose-binding 2 (LMAN2), Monoclonal Antibody

Full Product Name

Lectin, Mannose-binding 2 (LMAN2, Vesicular Integral-membrane Protein VIP36 Precursor)

Product Gene Name

anti-LMAN2 antibody

Product Synonym Names

Anti -Lectin, Mannose-binding 2 (LMAN2, Vesicular Integral-membrane Protein VIP36 Precursor)

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

8D116

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 7.4, 1% BSA and 0.05% sodium azide.

Purity/Purification

Affinity Purified
Purified using Protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (~95%) fetal bovine serum.

Specificity

Recognizes human EVI1.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

40,229 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (176758563..176778885, complement). Location: 5q35.3

OMIM

609551

3D Structure

ModBase 3D Structure for Q12907

Immunogen

Partial sequence of recombinant full-length protein to human EVI1

Product Categories/Family for anti-LMAN2 antibody

Antibodies; Abs to Lectins

Applications Tested/Suitable for anti-LMAN2 antibody

Western Blot (WB)

Application Notes for anti-LMAN2 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-LMAN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LMAN2 purchase

MBS600830 is an antibody targeting LMAN2. Also known as Lectin, Mannose-binding 2 (LMAN2, Vesicular Integral-membrane Protein VIP36 Precursor). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LMAN2. It may not necessarily be applicable to this product.

NCBI GI #

16878112

NCBI GeneID

10960

UniProt Primary Accession #

Q12907

UniProt Secondary Accession #

Q53HH1

UniProt Related Accession #

Q12907

NCBI Official Full Name

Lectin, mannose-binding 2

NCBI Official Synonym Full Names

lectin, mannose-binding 2

NCBI Official Symbol

LMAN2

NCBI Official Synonym Symbols

GP36B; VIP36; C5orf8

UniProt Protein Name

Vesicular integral-membrane protein VIP36

UniProt Synonym Protein Names

Glycoprotein GP36b; Lectin mannose-binding 2; Vesicular integral-membrane protein 36

Protein Family

Vesicular integral-membrane protein

UniProt Gene Name

LMAN2

UniProt Synonym Gene Names

C5orf8

UniProt Entry Name

LMAN2_HUMAN

NCBI Protein Information

vesicular integral-membrane protein VIP36; OTTHUMP00000161453; OTTHUMP00000223591; OTTHUMP00000223592; OTTHUMP00000223593; glycoprotein GP36b; vesicular integral protein of 36 kDa; vesicular integral-membrane protein 36

NCBI Summary for LMAN2

This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq]

UniProt Comments for LMAN2

LMAN2: Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: Golgi membrane; Golgi apparatus; extracellular space; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; cell surface; integral to plasma membrane; ER-Golgi intermediate compartment

Molecular Function: mannose binding; heat shock protein binding; metal ion binding; carbohydrate binding; glycoprotein binding

Biological Process: protein transport; positive regulation of phagocytosis; retrograde vesicle-mediated transport, Golgi to ER

Research Articles on LMAN2

1. Results identify the glycoprotein alpha1-antitrypsin as a cargo of VIP36.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LMAN2 antibody

Products by Pathway	Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram

Organs/Tissues associated with anti-LMAN2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with LMAN2 and Kidney
Blood Antibodies	>1 publications with LMAN2 and Blood
Liver Antibodies	>1 publications with LMAN2 and Liver