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Crooked Neck-Like 1 (CRNKL1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS600845

MBS600845 is an antibody targeting CRNKL1. Also known as Crooked Neck-Like 1 (CRNKL1, hCRN, MSTP021). Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Crooked Neck-Like 1 (CRNKL1), Monoclonal Antibody
Full Product Name
Crooked Neck-Like 1 (CRNKL1, hCRN, MSTP021)
Product Gene Name
Product Synonym Names
Anti -Crooked Neck-Like 1 (CRNKL1, hCRN, MSTP021)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C87
Host
Mouse
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Crooked Neck-Like 1.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
100,452 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (20015012..20036690, complement). Location: 20p11.2
OMIM
610952
3D Structure
ModBase 3D Structure for Q9BZJ0
Immunogen
Partial sequence of recombinant full-length protein to human Crooked Neck-Like 1

Product Categories/Family for anti-CRNKL1 antibody

Applications Tested/Suitable for anti-CRNKL1 antibody
Western Blot (WB)
Application Notes for anti-CRNKL1 antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

Testing Data of anti-CRNKL1 antibody

Mouse Anti-CRNKL1 Monoclonal Antibody – Cat# MBS600845

Other Notes

Small volumes of anti-CRNKL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRNKL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
crooked neck-like protein 1
NCBI Official Synonym Full Names
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
NCBI Official Symbol
CRNKL1
NCBI Official Synonym Symbols
CLF; CRN; Clf1; HCRN; SYF3; MSTP021
UniProt Protein Name
Crooked neck-like protein 1
UniProt Synonym Protein Names
Crooked neck homolog
UniProt Gene Name
CRNKL1
UniProt Synonym Gene Names
CRN
UniProt Entry Name
CRNL1_HUMAN
NCBI Protein Information
crooked neck-like protein 1; OTTHUMP00000030376; OTTHUMP00000063214; OTTHUMP00000226341; crooked neck-like 1; crooked neck homolog; Crn, crooked neck-like 1

NCBI Summary for CRNKL1

The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing. [provided by RefSeq]
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UniProt Comments for CRNKL1

CRNKL1: Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: spliceosome; cytoplasm; nuclear speck

Molecular Function: protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosome assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CRNKL1 antibody

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