Rabbit Anti-CACUL1 Polyclonal Antibody – Cat# MBS6009372

Immunoprecipitation of C10orf46 transfected lysate using C10orf46 rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with C10orf46 mouse polyclonal antibody.

C10orf46 (CACUL1) Antibody – Rabbit Polyclonal

Name: CACUL1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6009372
Price: 970 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6009372

Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. More details

$970 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

C10orf46 (CACUL1), Polyclonal Antibody

Full Product Name

C10orf46 (CACUL1, CAC1, CDK2-associated and Cullin Domain-containing Protein 1, Cdk-associated Cullin1, FLJ40409, MGC33215)

Product Gene Name

anti-CACUL1 antibody

Product Synonym Names

Anti -C10orf46 (CACUL1, CAC1, CDK2-associated and Cullin Domain-containing Protein 1, Cdk-associated Cullin1, FLJ40409, MGC33215)

Immunogen Sequence

MEESMEEEEG GSYEAMMDDQ NHNNWEAAVD GFRQPLPPPP PPSSIPAPAR EPPGGQLLAV PAVSVDRKGP KEGLPMGPQP PPEANGVIMM LKSCDAAAAV AKAAPAPTAS STININTSTS KFLMNVITIE DYKSTYWPKL DGAIDQLLTQ SPGDYIPISY EQIYSCVYKC VCQQHSEQMY SDLIKKITNH LERVSKELQA SPPDLYIERF NIALGQYMGA LQSIVPLFIY MNKFYIETKL NRDLKDDLIK LFTEHVAEKH IYSLMPLLLE AQSTPFQVTP STMANIVKGL YTLRPVSQNF TAV

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid.

Purity/Purification

Serum
Serum

Specificity

Recognizes human C10orf46.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,064 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (120433679..120514758, complement). Location: 10q26.11

3D Structure

ModBase 3D Structure for Q86Y37

Immunogen

Full length human C10orf46, aa1-303 (AAH38294.1).

Product Categories/Family for anti-CACUL1 antibody

Antibodies; Abs to Cullin

Applications Tested/Suitable for anti-CACUL1 antibody

Immunoprecipitation (IP)

Application Notes for anti-CACUL1 antibody

Suitable for use in Immunoprecipitation.

Other Notes

Small volumes of anti-CACUL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CACUL1 purchase

MBS6009372 is an antibody targeting CACUL1. Also known as C10orf46 (CACUL1, CAC1, CDK2-associated and Cullin Domain-containing Protein 1, Cdk-associated Cullin1, FLJ40409, MGC33215). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CACUL1. It may not necessarily be applicable to this product.

NCBI GI #

109452597

NCBI GeneID

143384

NCBI Accession #

NP_722517.3

UniProt Primary Accession #

Q86Y37

UniProt Secondary Accession #

Q5XPL7; Q8IY11; Q8N7S4

UniProt Related Accession #

Q86Y37

GenBank Nucleotide #

NM_153810.4

NCBI Official Full Name

CDK2-associated and cullin domain-containing protein 1

NCBI Official Synonym Full Names

CDK2-associated, cullin domain 1

NCBI Official Symbol

CACUL1

NCBI Official Synonym Symbols

CAC1; C10orf46

UniProt Protein Name

CDK2-associated and cullin domain-containing protein 1

UniProt Synonym Protein Names

Cdk-associated cullin1

Protein Family

CDK2-associated and cullin domain-containing protein

UniProt Gene Name

CACUL1

UniProt Synonym Gene Names

C10orf46; CAC1

UniProt Entry Name

CACL1_HUMAN

NCBI Protein Information

CDK2-associated and cullin domain-containing protein 1; Cdk-Associated Cullin1

UniProt Comments for CACUL1

CACUL1: Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. Belongs to the cullin family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q26.11

Cellular Component: cullin-RING ubiquitin ligase complex

Molecular Function: protein binding; ubiquitin protein ligase binding; protein kinase binding

Biological Process: ubiquitin-dependent protein catabolic process; positive regulation of protein kinase activity; positive regulation of cell proliferation; G1/S transition of mitotic cell cycle

Research Articles on CACUL1

1. High CAC1 expression is associated with cisplatin resistance in gastric cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.