Mouse Anti-RRAGD Polyclonal Antibody – Cat# MBS6009381

Western Blot analysis of RRAGD expression in transfected 293T cell line using MBS6009381 Lane 1: RRAGD transfected lysate (44kD). Lane 2: Non-transfected lysate.

RRAGD Antibody – Mouse Polyclonal

Name: RRAGD Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6009381
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6009381

MBS6009381 is an antibody targeting RRAGD. Also known as RRAGD (Ras-related GTP-binding Protein D, Rag D, RagD, bA11D8.2.1). Reactive in Human. Host: Mouse. More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RRAGD, Polyclonal Antibody

Full Product Name

RRAGD (Ras-related GTP-binding Protein D, Rag D, RagD, bA11D8.2.1)

Product Gene Name

anti-RRAGD antibody

Product Synonym Names

Anti -RRAGD (Ras-related GTP-binding Protein D, Rag D, RagD, bA11D8.2.1)

Immunogen Sequence

MSQVLGKPQP QDEDDAEEEE EEDELVGLAD YGDGPDSSDA DPDSGTEEGV LDFSDPFSTE VKPRILLMGL RRSGKSSIQK VVFHKMSPNE TLFLESTNKI CREDVSNSSF VNFQIWDFPG QIDFFDPTFD YEMIFRGTGA LIFVIDSQDD YMEALARLHL TVTRAYKVNT DINFEVFIHK VDGLSDDHKI ETQRDIHQRA NDDLADAGLE KIHLSFYLTS IYDHSIFEAF SKVVQKLIPQ LPTLENLLNI FISNSGIEKA FLFDVVSKIY IATDSTPVDM QTYELCCDMI DVVIDISCIY GLKEDGAGTP YDKESTAIIK LNNTTVLYLK EVTKFLALVC FVREESFERK GLIDYNFHCF RKAIHEVFEV RMKVVKSRKV QNRLQKKKRA TPNGTPRVLL

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human RRAGD.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

45,588 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (90074335..90121995, complement). Location: 6q15-q16

OMIM

608268

3D Structure

ModBase 3D Structure for Q9NQL2

Immunogen

Full length human RRAGD, aa1-400 (NP_067067.1).

Product Categories/Family for anti-RRAGD antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RRAGD antibody

Western Blot (WB)

Application Notes for anti-RRAGD antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-RRAGD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RRAGD. It may not necessarily be applicable to this product.

NCBI GI #

11034847

NCBI GeneID

58528

NCBI Accession #

NP_067067.1

UniProt Primary Accession #

Q9NQL2

UniProt Secondary Accession #

Q7L8F9; Q9NPG0; A8K184

UniProt Related Accession #

Q9NQL2

GenBank Nucleotide #

NM_021244.4

NCBI Official Full Name

ras-related GTP-binding protein D

NCBI Official Synonym Full Names

Ras-related GTP binding D

NCBI Official Symbol

RRAGD

NCBI Official Synonym Symbols

RAGD; bA11D8.2.1

UniProt Protein Name

Ras-related GTP-binding protein D

Protein Family

Ras-related GTP-binding protein

UniProt Gene Name

RRAGD

UniProt Synonym Gene Names

Rag D; RagD

UniProt Entry Name

RRAGD_HUMAN

NCBI Protein Information

ras-related GTP-binding protein D; Rag D protein

NCBI Summary for RRAGD

RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]

UniProt Comments for RRAGD

RRAGD: Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity. Probably required for the amino acid- induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB. Belongs to the GTR/RAG GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: lysosome; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein heterodimerization activity

Biological Process: metabolic process; regulation of autophagy; cellular response to starvation; positive regulation of TOR signaling pathway

Research Articles on RRAGD

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RRAGD antibody

Reference Product	PubMed Publications
RRAGC antibody	>3 publications with RRAGD and RRAGC
RRAGA antibody	>2 publications with RRAGD and RRAGA
NOL8 antibody	>1 publications with RRAGD and NOL8
RRAGB antibody	>1 publications with RRAGD and RRAGB
RPTOR antibody	>1 publications with RRAGD and RPTOR
MTOR antibody	>1 publications with RRAGD and MTOR

Pathways associated with anti-RRAGD antibody

Products by Pathway	Pathway Diagram
TOR Signaling Pathway antibodies	TOR Signaling Pathway Diagram
MTOR Signaling Pathway antibodies	MTOR Signaling Pathway Diagram
MTOR Signaling Pathway antibodies	MTOR Signaling Pathway Diagram

Diseases associated with anti-RRAGD antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with RRAGD and Neoplasms
Heart Diseases Antibodies	>1 publications with RRAGD and Heart Diseases
Disease Models, Animal Antibodies	>1 publications with RRAGD and Disease Models, Animal
Cardiovascular Diseases Antibodies	>1 publications with RRAGD and Cardiovascular Diseases

Organs/Tissues associated with anti-RRAGD antibody

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>1 publications with RRAGD and Connective Tissue
Blood Antibodies	>1 publications with RRAGD and Blood
Intestine Antibodies	>1 publications with RRAGD and Intestine
Skin Antibodies	>1 publications with RRAGD and Skin
Heart Antibodies	>1 publications with RRAGD and Heart