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NOTCH2NL Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6010720

May function in the Notch signaling pathway and regulate neutrophil differentiation. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NOTCH2NL, Monoclonal Antibody
Full Product Name
NOTCH2NL (Notch Homolog 2 N-terminal-like Protein, N2N, FLJ35032, FLJ55807)
Product Gene Name
Product Synonym Names
Anti -NOTCH2NL (Notch Homolog 2 N-terminal-like Protein, N2N, FLJ35032, FLJ55807)
Immunogen Sequence
MCVTYHNGTG YCKCPEGFLG EYCQHRDPCE KNRCQNGGTC VAQAMLGKAT CRCASGFTGE DCQYSTSHPC FVSRPCLNGG TCHMLSRDTY ECTCQVGFTG KECQWTDACL SHPCANGSTC TTVANQFSCK CLTGFTGQKC ETDVNECDIP GHCQHGGICL NLPGSYQCQC LQGFTGQYCD SLYVPCAPSP CVNGGTCRQT GDFTFECNCL PETVRRGTEL WERDREVWNG KEHDEN*
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2G12-2A5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NOTCH2NL.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,835 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (145176379..145286270). Location: 1q21.2
3D Structure
ModBase 3D Structure for Q7Z3S9
Immunogen
Full length recombinant protein corresponding to aa1-237 from human NOTCH2NL (AAH19835) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-NOTCH2NL antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-NOTCH2NL antibody
Suitable for use in Immunofluorescence, ELISA and Western Blot.
Dilution: Immunofluorescence: 10ug/ml
Sandwich ELISA: The detection limit is ~0.1ng/ml as a capture antibody.

Western Blot (WB) of anti-NOTCH2NL antibody

Western Blot detection against Immunogen (52.07kD).
Mouse Anti-NOTCH2NL Monoclonal Antibody – Cat# MBS6010720

Western Blot (WB) of anti-NOTCH2NL antibody

NOTCH2NL monoclonal antibody Western Blot analysis of NOTCH2NL expression in HL-60.
Mouse Anti-NOTCH2NL Monoclonal Antibody, Western Blot (WB) – Cat# MBS6010720

Immunofluorescence (IF) of anti-NOTCH2NL antibody

Immunofluorescence of monoclonal antibody to NOTCH2NL on HeLa cell. [antibody concentration 10ug/ml]
Mouse Anti-NOTCH2NL Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6010720

Testing Data of anti-NOTCH2NL antibody

Detection limit for recombinant GST tagged NOTCH2NL is ~0.1ng/ml as a capture antibody.
Mouse Anti-NOTCH2NL Monoclonal Antibody, Testing Data – Cat# MBS6010720

Other Notes

Small volumes of anti-NOTCH2NL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NOTCH2NL purchase

MBS6010720 is an antibody targeting NOTCH2NL. Also known as NOTCH2NL (Notch Homolog 2 N-terminal-like Protein, N2N, FLJ35032, FLJ55807). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NOTCH2NL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
notch homolog 2 N-terminal-like protein
NCBI Official Synonym Full Names
notch 2 N-terminal like
NCBI Official Symbol
NOTCH2NL
NCBI Official Synonym Symbols
N2N
UniProt Protein Name
Notch homolog 2 N-terminal-like protein
UniProt Gene Name
NOTCH2NL
UniProt Synonym Gene Names
N2N
UniProt Entry Name
NT2NL_HUMAN
NCBI Protein Information
notch homolog 2 N-terminal-like protein; Notch homolog 2 N-terminal like protein

UniProt Comments for NOTCH2NL

NOTCH2NL: May function in the Notch signaling pathway and regulate neutrophil differentiation. Belongs to the NOTCH family. Interacts with ELANE. 3 isoforms of the human protein are produced by alternative splicing

Chromosomal Location of Human Ortholog: 1q21.2

Cellular Component: cytoplasm; extracellular region

Molecular Function: calcium ion binding

Biological Process: Notch signaling pathway; multicellular organismal development; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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