Rabbit Anti-SLC15A1 Polyclonal Antibody – Cat# MBS6011274

Human Small Intestine, Paneth Cells (formalin-fixed, paraffin-embedded) stained with SLC15A1 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.

SLC15A1 Antibody – Rabbit Polyclonal

Name: SLC15A1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6011274
Price: 935 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6011274

Proton-coupled intake of oligopeptides of 2 to 4aa with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. More details

$935 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC15A1, Polyclonal Antibody

Full Product Name

SLC15A1, CT (Solute Carrier Family 15 Member 1, Intestinal H(+)/Peptide Cotransporter, Oligopeptide Transporter, Small Intestine Isoform, Peptide Transporter 1, PEPT1)

Product Gene Name

anti-SLC15A1 antibody

Product Synonym Names

Anti -SLC15A1, CT (Solute Carrier Family 15 Member 1, Intestinal H(+)/Peptide Cotransporter, Oligopeptide Transporter, Small Intestine Isoform, Peptide Transporter 1, PEPT1)

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human SLC15A1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

78,806 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (99336055..99404929, complement). Location: 13q32.3

OMIM

600544

3D Structure

ModBase 3D Structure for P46059

Immunogen

Synthetic peptide corresponding to human SLC15A1 at C-terminal (KLH).

Product Categories/Family for anti-SLC15A1 antibody

Antibodies; Abs to Ion Channel

Applications Tested/Suitable for anti-SLC15A1 antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-SLC15A1 antibody

Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1ug/ml
Western Blot: 1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml

Other Notes

Small volumes of anti-SLC15A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC15A1 purchase

MBS6011274 is an antibody targeting SLC15A1. Also known as SLC15A1, CT (Solute Carrier Family 15 Member 1, Intestinal H(+)/Peptide Cotransporter, Oligopeptide Transporter, Small Intestine Isoform, Peptide Transporter 1, PEPT1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC15A1. It may not necessarily be applicable to this product.

NCBI GI #

4827008

NCBI GeneID

6564

NCBI Accession #

NP_005064.1

UniProt Primary Accession #

P46059

UniProt Secondary Accession #

Q5VW82

UniProt Related Accession #

P46059

GenBank Nucleotide #

NM_005073.3

NCBI Official Full Name

solute carrier family 15 member 1

NCBI Official Synonym Full Names

solute carrier family 15 (oligopeptide transporter), member 1

NCBI Official Symbol

SLC15A1

NCBI Official Synonym Symbols

PEPT1; HPECT1; HPEPT1

UniProt Protein Name

Solute carrier family 15 member 1

UniProt Synonym Protein Names

Intestinal H(+)/peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1

Protein Family

Solute carrier family

UniProt Gene Name

SLC15A1

UniProt Synonym Gene Names

PEPT1

UniProt Entry Name

S15A1_HUMAN

NCBI Protein Information

solute carrier family 15 member 1; peptide transporter 1; Caco-2 oligopeptide transporter; intestinal H+/peptide cotransporter; macrophage oligopeptide transporter PEPT1; oligopeptide transporter, small intestine isoform

NCBI Summary for SLC15A1

This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010]

UniProt Comments for SLC15A1

SLC15A1: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Belongs to the PTR2/POT transporter (TC 2.A.17) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q32.3

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: proton-dependent oligopeptide secondary active transmembrane transporter activity; peptide:hydrogen symporter activity

Biological Process: proton transport; protein transport; transport; digestion; ion transport; transmembrane transport

Research Articles on SLC15A1

1. These studies unequivocally demonstrate the presence of PEPT1 protein in healthy distal colonic epithelium in mice, rats, and humans and proved that the protein is functional and contributes to electrolyte and water handling in mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC15A1 antibody

Reference Product	PubMed Publications
SLC36A1 antibody	>6 publications with SLC15A1 and SLC36A1
CDH17 antibody	>6 publications with SLC15A1 and CDH17
CDX2 antibody	>5 publications with SLC15A1 and CDX2
SLCO2B1 antibody	>4 publications with SLC15A1 and SLCO2B1
SLC22A8 antibody	>2 publications with SLC15A1 and SLC22A8
PDZK1 antibody	>1 publications with SLC15A1 and PDZK1

Pathways associated with anti-SLC15A1 antibody

Products by Pathway	Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Proton/oligonucleotide Cotransporters Pathway antibodies	Proton/oligonucleotide Cotransporters Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies	Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with anti-SLC15A1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>22 publications with SLC15A1 and Inflammation
Neoplasms Antibodies	>22 publications with SLC15A1 and Neoplasms
Kidney Diseases Antibodies	>8 publications with SLC15A1 and Kidney Diseases
Diabetes Mellitus Antibodies	>8 publications with SLC15A1 and Diabetes Mellitus
Renal Insufficiency Antibodies	>5 publications with SLC15A1 and Renal Insufficiency
Weight Loss Antibodies	>5 publications with SLC15A1 and Weight Loss
Liver Diseases Antibodies	>4 publications with SLC15A1 and Liver Diseases
Diarrhea Antibodies	>4 publications with SLC15A1 and Diarrhea
Necrosis Antibodies	>4 publications with SLC15A1 and Necrosis
Hyperglycemia Antibodies	>4 publications with SLC15A1 and Hyperglycemia

Organs/Tissues associated with anti-SLC15A1 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>205 publications with SLC15A1 and Intestine
Muscle Antibodies	>3 publications with SLC15A1 and Muscle