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ARID3A Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6011962

Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARID3A, Polyclonal Antibody
Full Product Name
ARID3A (AT-rich Interactive Domain-containing Protein 3A, ARID Domain-containing Protein 3A, B-cell Regulator of IgH Transcription, Bright, Dead Ringer-like Protein 1, E2F-binding Protein 1, DRIL1, DRIL3, DRX, E2FBP1)
Product Gene Name
anti-ARID3A antibody
Product Synonym Names
Anti -ARID3A (AT-rich Interactive Domain-containing Protein 3A, ARID Domain-containing Protein 3A, B-cell Regulator of IgH Transcription, Bright, Dead Ringer-like Protein 1, E2F-binding Protein 1, DRIL1, DRIL3, DRX, E2FBP1)
Immunogen Sequence
MKLQAVMETL LQRQQRARQE LEARQQLPPD PPAAPHGRAR AAPDEDREPE SARMQRAQMA ALAAMRAAAA GLGHPASPGG SEDGPPGSEE EDAAREGTPG SPGRGREGPG EEHFEDMASD EDMKPKWEEE EMEEDLGEDE EEEEEDYEDE EEEEDEEGLG PPGPASLGTT ALFPRKAQPP QAFRGDGVPR VLGGQERPGP GPAHPGGAAH VAPQLQPPDH GDWTYEEQFK QLYELDGDPK RKEFLDDLFS FMQKRGTPVN RIPIMAKQVL DLFMLYVLVT EKGGLVEVIN KKLWREITKG LNLPTSITSA AFTLRTQYME YLYPYECEKR GLSNPNELQA AIDSNRREGR RQSFGGSLFA YSPGGAHGML SSPKLPVSSL GLAASTNGSS ITPAPKIKKE EDSAIPITVP GRLPVSLAGH PVVAAQAAAV QAAAAQAAVA AQAAALEQLR EKLESAEPPE KKMALVADEQ QRLMQRALQQ NFLAMAAQLP MSIRINSQAS ESRQDSAVNL TGTNGSNSIS MSVEINGIMY TGVLFAQPPA PTPTSAPNKG GGGGGSSSSN AGGRGGNTGT SGGQAGPAGL STPSTSTSNN SLP
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ARID3A.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
62,889 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (925733..972816). Location: 19p13.3
OMIM
603265
3D Structure
ModBase 3D Structure for Q99856
Immunogen
Full length human ARID3A, aa1-593 (AAH60828.1).

Product Categories/Family for anti-ARID3A antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-ARID3A antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ARID3A antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-ARID3A antibody

Western Blot analysis of ARID3A expression in transfected 293T cell line by ARID3A polyclonal antibody. Lane 1: ARID3A transfected lysate (65.23kD). Lane 2: Non-transfected lysate.
Mouse Anti-ARID3A Polyclonal Antibody – Cat# MBS6011962

Immunofluorescence (IF) of anti-ARID3A antibody

Immunofluorescence of purified antibody to ARID3A on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-ARID3A Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6011962

Other Notes

Small volumes of anti-ARID3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARID3A purchase

MBS6011962 is an antibody targeting ARID3A. Also known as ARID3A (AT-rich Interactive Domain-containing Protein 3A, ARID Domain-containing Protein 3A, B-cell Regulator of IgH Transcription, Bright, Dead Ringer-like Protein 1, E2F-binding Protein 1, DRIL1, DRIL3, DRX, E2FBP1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ARID3A. It may not necessarily be applicable to this product.

NCBI GI #
4885193
NCBI GeneID
1820
NCBI Accession #
NP_005215.1
UniProt Primary Accession #
Q99856
UniProt Secondary Accession #
Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3
UniProt Related Accession #
Q99856
GenBank Nucleotide #
NM_005224.2
NCBI Official Full Name
AT-rich interactive domain-containing protein 3A
NCBI Official Synonym Full Names
AT rich interactive domain 3A (BRIGHT-like)
NCBI Official Symbol
ARID3A
NCBI Official Synonym Symbols
DRIL1; DRIL3; BRIGHT; E2FBP1
UniProt Protein Name
AT-rich interactive domain-containing protein 3A
UniProt Synonym Protein Names
B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1
Protein Family
AT-rich interactive domain-containing protein
UniProt Gene Name
ARID3A
UniProt Synonym Gene Names
DRIL1; DRIL3; DRX; E2FBP1; ARID domain-containing protein 3A; Bright
UniProt Entry Name
ARI3A_HUMAN
NCBI Protein Information
AT-rich interactive domain-containing protein 3A; dead ringer-like 1; E2F-binding protein 1; ARID domain-containing 3A; dead ringer-like protein 1; ARID domain-containing protein 3A; B-cell regulator of IgH transcription; AT rich interactive domain 3A (BRIGHT- like) protein

NCBI Summary for ARID3A

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
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UniProt Comments for ARID3A

Bright: a member of the ARID (AT-rich interaction domain) family of transcription factors. It was found by its homology to the Drosophila dead ringer protein, which is important for normal embryogenesis. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. Contributes to localized control of accessibility and therefore nonrandom gene use during V(D)J recombination.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; lipid raft

Molecular Function: protein binding; protein homodimerization activity; chromatin binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on ARID3A

1. miR-125b can act as an oncogene in B-cell acute lymphoblastic leukemia by targeting ARID3a and mediating its repression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARID3A antibody

 Reference Product  PubMed Publications
 E2F1 antibody  >7 publications with ARID3A and E2F1
 BTK antibody  >6 publications with ARID3A and BTK
 PML antibody  >4 publications with ARID3A and PML
 SP140 antibody  >1 publications with ARID3A and SP140
 TP53 antibody  >1 publications with ARID3A and TP53

Pathways associated with anti-ARID3A antibody

 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram

Diseases associated with anti-ARID3A antibody

 Disease Name  Pubmed Publications
 Translocation, Genetic Antibodies  >1 publications with ARID3A and Translocation, Genetic
 Brain Diseases Antibodies  >1 publications with ARID3A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with ARID3A and Kidney Diseases

Organs/Tissues associated with anti-ARID3A antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with ARID3A and Bone
 Ovary Antibodies  >1 publications with ARID3A and Ovary
 Liver Antibodies  >1 publications with ARID3A and Liver
 Kidney Antibodies  >1 publications with ARID3A and Kidney
 Lymph Node Antibodies  >1 publications with ARID3A and Lymph Node
 Embryonic Tissue Antibodies  >1 publications with ARID3A and Embryonic Tissue
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