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SNX27 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6011995

SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family… More details

$895 / 0.2 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SNX27, Polyclonal Antibody
Full Product Name
SNX27, ID (SNX27, KIAA0488, Sorting nexin-27)
Product Gene Name
Product Synonym Names
Anti -SNX27, ID (SNX27, KIAA0488, Sorting nexin-27)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
61,265 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (151584454..151671559). Location: 1q21.3
OMIM
611541
3D Structure
ModBase 3D Structure for Q96L92
Immunogen
SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319~349 amino acids from the Central region of human SNX27.
Applications Tested/Suitable for anti-SNX27 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SNX27 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-SNX27 antibody

Western blot analysis of SNX27 Antibody (Center) in 293 cell line lysates (35ug/lane). SNX27 (arrow) was detected using the purified Pab.
Rabbit Anti-SNX27 Polyclonal Antibody – Cat# MBS6011995

Other Notes

Small volumes of anti-SNX27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNX27 purchase

MBS6011995 is an antibody targeting SNX27. Also known as SNX27, ID (SNX27, KIAA0488, Sorting nexin-27). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SNX27. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sorting nexin-27
NCBI Official Synonym Full Names
sorting nexin family member 27
NCBI Official Symbol
SNX27
NCBI Official Synonym Symbols
MRT1; MY014
UniProt Protein Name
Sorting nexin-27
Protein Family
UniProt Gene Name
SNX27
UniProt Synonym Gene Names
KIAA0488
UniProt Entry Name
SNX27_HUMAN
NCBI Protein Information
sorting nexin-27; methamphetamine-responsive transcript 1

NCBI Summary for SNX27

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for SNX27

SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; early endosome membrane; retromer complex; cytoplasm; early endosome; immunological synapse; cytosol

Molecular Function: protein binding; phosphatidylinositol 3-phosphate binding

Biological Process: intracellular protein transport; establishment of natural killer cell polarity; endosome to lysosome transport; endosome transport; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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