Mouse Anti-PPP2R5C Monoclonal Antibody – Cat# MBS601308

Protein Phosphatase 2a, B56 Gamma (PPP2R5C) Antibody – Mouse Monoclonal

Name: PPP2R5C Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS601308
Price: 910 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601308

Protein phosphatase type 2A (PP2A) is a major eukaryotic serine/threonine protein phosphatase (PPase). PP2A is highly conserved and often exist as a heterotrimeric enzyme composed of a catalytic (C) subunit, a structural (A) subunit, and a variable… More details

$910 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Protein Phosphatase 2A, B56 gamma (Ppp2r5c), Monoclonal Antibody

Full Product Name

Protein Phosphatase 2A, B56 gamma (PP2g)

Product Gene Name

anti-Ppp2r5c antibody

Product Synonym Names

Anti -Protein Phosphatase 2A, B56 gamma (PP2g)

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

7C5

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Specific for the gamma isoform of the human B (or B56) regulatory subunit of protein phosphatase 2A (PP2A).

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

11,045 Da

Chromosome Location

Chromosome: 12; NC_000078.5 (111685389..111821271). Location: 12 F1; 12 57.0 cM

3D Structure

ModBase 3D Structure for Q3TSR8

Immunogen

Full-length human PP2A B56 gamma fusion protein, which is 90% homologous with mouse and rat.

Positive Control

PP2A B56gamma-transfected 293T cell lysates.

Product Categories/Family for anti-Ppp2r5c antibody

Antibodies; Abs to Enzymes; Phosphatase

Applications Tested/Suitable for anti-Ppp2r5c antibody

Western Blot (WB)

Application Notes for anti-Ppp2r5c antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 1-3ug/ml. Detects a band of ~60kD in human PP2A B56 -transfected 293T cell lysates.
Optimal working dilutions to be determined by researcher.

Other Notes

Small volumes of anti-Ppp2r5c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ppp2r5c purchase

MBS601308 is an antibody targeting Ppp2r5c. Also known as Protein Phosphatase 2A, B56 gamma (PP2g). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Ppp2r5c. It may not necessarily be applicable to this product.

NCBI GI #

12862390

NCBI GeneID

26931

UniProt Primary Accession #

Q3TSR8

UniProt Related Accession #

Q3TSR8; Q60996; Q6ZQK4; Q8C8H4

NCBI Official Full Name

protein phosphatase 2A B56 regulatory subunit gamma 2 isoform

NCBI Official Synonym Full Names

protein phosphatase 2, regulatory subunit B (B56), gamma isoform

NCBI Official Symbol

Ppp2r5c

NCBI Official Synonym Symbols

C85228; AI060890; AW545884; mKIAA0044; D12Bwg0916e; 2610043M05Rik; 2700063L20Rik

UniProt Protein Name

Putative uncharacterized protein

Protein Family

Serine/threonine-protein phosphatase

UniProt Gene Name

Ppp2r5c

UniProt Entry Name

Q3TSR8_MOUSE

NCBI Protein Information

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform; Band 8A; B56/PP2A gamma; PP2A B subunit isoform B'-gamma; PP2A B subunit isoform R5-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform B'-alpha-3; PP2A B subunit isoform PR61-gamma

UniProt Comments for Ppp2r5c

PPP2R5C: a regulatory subunit of PP2A that might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.Three alternatively spliced human isoforms have been described.

Protein type: Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Cellular Component: protein phosphatase type 2A complex; chromosome; nucleus; chromosome, pericentric region

Molecular Function: protein binding; protein phosphatase type 2A regulator activity

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; signal transduction

Research Articles on Ppp2r5c

1. results suggest that Ppp2r5c expression is regulated by Nrl during retinogenesis through direct binding to the promoter region of Ppp2r5c

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Ppp2r5c antibody

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Costimulation By The CD28 Family Pathway antibodies	Costimulation By The CD28 Family Pathway Diagram
DNA Replication Pathway antibodies	DNA Replication Pathway Diagram
Degradation Of Beta-catenin By The Destruction Complex Pathway antibodies	Degradation Of Beta-catenin By The Destruction Complex Pathway Diagram
Glycogen Metabolism Pathway antibodies	Glycogen Metabolism Pathway Diagram
IL-6 Signaling Pathway antibodies	IL-6 Signaling Pathway Diagram
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Organs/Tissues associated with anti-Ppp2r5c antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with Ppp2r5c and Skin
Brain Antibodies	>1 publications with Ppp2r5c and Brain