Rabbit Anti-GNA13 Polyclonal Antibody – Cat# MBS6013094

GNA13 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GNA13 antibody detected the GNA13 protein (arrow).

GNA13 Antibody – Rabbit Polyclonal

Name: GNA13 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6013094
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6013094

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GNA13, Polyclonal Antibody

Full Product Name

GNA13, ID (GNA13, Guanine nucleotide-binding protein subunit alpha-13)

Product Gene Name

anti-GNA13 antibody

Product Synonym Names

Anti -GNA13, ID (GNA13, Guanine nucleotide-binding protein subunit alpha-13)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

44,050 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (63005407..63052920, complement). Location: 17q24.3

OMIM

604406

3D Structure

ModBase 3D Structure for Q14344

Immunogen

GNA13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-212 amino acids from the Central region of human GNA13.

Product Categories/Family for anti-GNA13 antibody

Antibodies; Abs to Binding Proteins

Applications Tested/Suitable for anti-GNA13 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-GNA13 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-GNA13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNA13 purchase

MBS6013094 is an antibody targeting GNA13. Also known as GNA13, ID (GNA13, Guanine nucleotide-binding protein subunit alpha-13). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GNA13. It may not necessarily be applicable to this product.

NCBI GI #

540344574

NCBI GeneID

10672

NCBI Accession #

NP_001269354.1

UniProt Primary Accession #

Q14344

UniProt Secondary Accession #

Q8TD70; B2R977

UniProt Related Accession #

Q14344

GenBank Nucleotide #

NM_001282425.1

NCBI Official Full Name

guanine nucleotide-binding protein subunit alpha-13 isoform 2

NCBI Official Synonym Full Names

guanine nucleotide binding protein (G protein), alpha 13

NCBI Official Symbol

GNA13

NCBI Official Synonym Symbols

G13

UniProt Protein Name

Guanine nucleotide-binding protein subunit alpha-13

Protein Family

Guanine nucleotide-binding protein

UniProt Gene Name

GNA13

UniProt Synonym Gene Names

G alpha-13

UniProt Entry Name

GNA13_HUMAN

NCBI Protein Information

guanine nucleotide-binding protein subunit alpha-13; g alpha-13; G-protein subunit alpha-13

UniProt Comments for GNA13

G-alpha 13: a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Activates Rho. Protein kinase A blocks Rho activation by phosphorylation of G-alpha(13). Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes.

Protein type: G protein, heterotrimeric; G protein; G protein, heterotrimeric alpha G(12)

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: focal adhesion; membrane; brush border membrane; plasma membrane; melanosome; heterotrimeric G-protein complex; nucleus

Molecular Function: GTPase activity; protein binding; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; type 1 angiotensin receptor binding; D5 dopamine receptor binding

Biological Process: platelet activation; phospholipase D activation; metabolic process; in utero embryonic development; signal transduction; G-protein signaling, adenylate cyclase activating pathway; regulation of cell migration; Rho protein signal transduction; patterning of blood vessels; regulation of cell shape; elevation of cytosolic calcium ion concentration; cell motility; blood coagulation; cell differentiation

Research Articles on GNA13

1. GNA13 is an important mediator of prostate cancer cell invasion, and miR-182 and miR-200 family members regulate its expression post-transcriptionally

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GNA13 antibody

Reference Product	PubMed Publications
GNA12 antibody	>3 publications with GNA13 and GNA12
CTNNB1 antibody	>1 publications with GNA13 and CTNNB1

Pathways associated with anti-GNA13 antibody

Products by Pathway	Pathway Diagram
CXCR4-mediated Signaling Events Pathway antibodies	CXCR4-mediated Signaling Events Pathway Diagram
G Protein Signaling Pathways antibodies	G Protein Signaling Pathways Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
G13 Signaling Pathway antibodies	G13 Signaling Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
LPA Receptor Mediated Events Pathway antibodies	LPA Receptor Mediated Events Pathway Diagram
Long-term Depression Pathway antibodies	Long-term Depression Pathway Diagram
Long-term Depression Pathway antibodies	Long-term Depression Pathway Diagram
Plasma Membrane Estrogen Receptor Signaling Pathway antibodies	Plasma Membrane Estrogen Receptor Signaling Pathway Diagram

Diseases associated with anti-GNA13 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with GNA13 and Neoplasms
Immune System Diseases Antibodies	>3 publications with GNA13 and Immune System Diseases
Death Antibodies	>1 publications with GNA13 and Death
Neoplasm Metastasis Antibodies	>1 publications with GNA13 and Neoplasm Metastasis
Burkitt Lymphoma Antibodies	>1 publications with GNA13 and Burkitt Lymphoma

Organs/Tissues associated with anti-GNA13 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with GNA13 and Bone
Vascular Antibodies	>1 publications with GNA13 and Vascular
Prostate Antibodies	>1 publications with GNA13 and Prostate
Blood Antibodies	>1 publications with GNA13 and Blood
Lung Antibodies	>1 publications with GNA13 and Lung
Embryonic Tissue Antibodies	>1 publications with GNA13 and Embryonic Tissue
Testis Antibodies	>1 publications with GNA13 and Testis
Placenta Antibodies	>1 publications with GNA13 and Placenta
Brain Antibodies	>1 publications with GNA13 and Brain