Rabbit Anti-SGIP1 Polyclonal Antibody – Cat# MBS6013297

SGIP1 Antibody (N-term) western blot analysis in CHO,MDA-MB231, mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SGIP1 antibody detected the SGIP1 protein (arrow).

SGIP1 Antibody – Rabbit Polyclonal

Name: SGIP1 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6013297
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6013297

SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SGIP1, Polyclonal Antibody

Full Product Name

SGIP1, NT (SGIP1, SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein)

Product Gene Name

anti-SGIP1 antibody

Product Synonym Names

Anti -SGIP1, NT (SGIP1, SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human, mouse

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

89,109 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (66999066..67210768). Location: 1p31.3

OMIM

611540

3D Structure

ModBase 3D Structure for Q9BQI5

Immunogen

SGIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human SGIP1.

Product Categories/Family for anti-SGIP1 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-SGIP1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-SGIP1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-SGIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGIP1 purchase

MBS6013297 is an antibody targeting SGIP1. Also known as SGIP1, NT (SGIP1, SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SGIP1. It may not necessarily be applicable to this product.

NCBI GI #

116235472

NCBI GeneID

84251

NCBI Accession #

NP_115667.2

UniProt Primary Accession #

Q9BQI5

UniProt Secondary Accession #

Q4LE32; Q5VYE2; Q5VYE3; Q5VYE4; Q68D76; Q6MZY6; Q8IWC2; A6NL81; A6NLD1

UniProt Related Accession #

Q9BQI5

GenBank Nucleotide #

NM_032291.2

NCBI Official Full Name

SH3-containing GRB2-like protein 3-interacting protein 1

NCBI Official Synonym Full Names

SH3-domain GRB2-like (endophilin) interacting protein 1

NCBI Official Symbol

SGIP1

UniProt Protein Name

SH3-containing GRB2-like protein 3-interacting protein 1

UniProt Synonym Protein Names

Endophilin-3-interacting protein

Protein Family

SH3-containing GRB2-like protein 3-interacting protein

UniProt Gene Name

SGIP1

UniProt Entry Name

SGIP1_HUMAN

NCBI Protein Information

SH3-containing GRB2-like protein 3-interacting protein 1; endophilin-3-interacting protein

UniProt Comments for SGIP1

SGIP1: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: clathrin-coated vesicle; cytoplasm; plasma membrane; AP-2 adaptor complex; coated pit

Molecular Function: protein binding; microtubule binding; phospholipid binding; SH3 domain binding

Biological Process: response to dietary excess; endocytosis; positive regulation of receptor-mediated endocytosis

Research Articles on SGIP1

1. Our results show association between genetic variants in SGIP1 and fat mass. We provide evidence that variation in SGIP1 is a potentially important determinant of obesity-related traits in humans

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SGIP1 antibody

Disease Name	Pubmed Publications
Weight Loss Antibodies	>1 publications with SGIP1 and Weight Loss
Inflammation Antibodies	>1 publications with SGIP1 and Inflammation

Organs/Tissues associated with anti-SGIP1 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>2 publications with SGIP1 and Nerve
Brain Antibodies	>2 publications with SGIP1 and Brain
Vascular Antibodies	>1 publications with SGIP1 and Vascular
Eye Antibodies	>1 publications with SGIP1 and Eye