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SEPT9 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6013300

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. More details

$880 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SEPT9, Polyclonal Antibody
Full Product Name
SEPT9 (Septin-9, MLL Septin-like Fusion Protein MSF-A, MLL Septin-like Fusion Protein, Ovarian/Breast Septin, Ov/Br Septin, Septin D1, KIAA0991, MSF)
Product Gene Name
anti-SEPT9 antibody
Product Synonym Names
Anti -SEPT9 (Septin-9, MLL Septin-like Fusion Protein MSF-A, MLL Septin-like Fusion Protein, Ovarian/Breast Septin, Ov/Br Septin, Septin D1, KIAA0991, MSF)
Immunogen Sequence
MERDRISALK RSFEVEEVET PNSTPPRRVQ TPLLRATVAS STQKFQDLGV KNSEPSARHV DSLSQRSPKA SLRRVELSGP KAAEPVSRRT ELSIDISSKQ VENAGAIGPS RFGLKRAEVL GHKTPEPAPR RTEITIVKPQ ESAHRRMEPP ASKVPEVPTA PATDAAPKRV EIQMPKPAEA PTAPSPAQTL ENSEPAPVSQ LQSRLEPKPQ PPVAEATPRS QEATEAAPSC VGDMADTPRD AGLKQAPASR NEKAPVDFGY VGIDSILEQM RRKAMKQGFE FNIMVVGQSG LGKSTLINTL FKSKISRKSV QPTSEERIPK TIEIKSITHD IEEKGVRMKL TVIDTPGFGD HINNENCWQP IMKFINDQYE KYLQEEVNIN RKKRIPDTRV HCCLYFIPAT GHSLRPLDIE FMKRLSKVVN IVPVIAKADT LTLEERVHFK QRITADLLSN GIDVYPQKEF DEDSEDRLVN EKFREMIPFA VVGSDHEYQV NGKRILGRKT KWGTIEVENT THCEFAYLRD LLIRTHMQNI KDITSSIHFE AYRVKRLNEG SSAMANGVEE KEPEAPEM
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SEPT9.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
65,401 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (75277492..75496678). Location: 17q25
OMIM
162100
3D Structure
ModBase 3D Structure for Q9UHD8
Immunogen
Full-length human SEPT9, aa1-568 (AAH21192.1).

Product Categories/Family for anti-SEPT9 antibody

Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-SEPT9 antibody
Western Blot (WB)
Application Notes for anti-SEPT9 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-SEPT9 antibody

SEPT9 polyclonal antibody. Western Blot analysis of SEPT9 expression in HepG2.
Mouse Anti-SEPT9 Polyclonal Antibody – Cat# MBS6013300

Western Blot (WB) of anti-SEPT9 antibody

Western Blot analysis of SEPT9 expression in transfected 293T cell line by SEPT9 polyclonal antibody. Lane 1: SEPT9 transfected lysate (62.48kD). Lane 2: Non-transfected lysate
Mouse Anti-SEPT9 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6013300

Other Notes

Small volumes of anti-SEPT9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEPT9 purchase

MBS6013300 is an antibody targeting SEPT9. Also known as SEPT9 (Septin-9, MLL Septin-like Fusion Protein MSF-A, MLL Septin-like Fusion Protein, Ovarian/Breast Septin, Ov/Br Septin, Septin D1, KIAA0991, MSF). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SEPT9. It may not necessarily be applicable to this product.

NCBI GI #
164698504
NCBI GeneID
10801
NCBI Accession #
NP_001106968.1
UniProt Primary Accession #
Q9UHD8
UniProt Secondary Accession #
Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654
UniProt Related Accession #
Q9UHD8
GenBank Nucleotide #
NM_001113496.1
NCBI Official Full Name
septin-9 isoform f
NCBI Official Synonym Full Names
septin 9
NCBI Official Symbol
SEPT9
NCBI Official Synonym Symbols
MSF; MSF1; NAPB; SINT1; PNUTL4; SeptD1; AF17q25
UniProt Protein Name
Septin-9
UniProt Synonym Protein Names
MLL septin-like fusion protein MSF-A; MLL septin-like fusion protein; Ovarian/Breast septin; Ov/Br septin; Septin D1
UniProt Gene Name
SEPT9
UniProt Synonym Gene Names
KIAA0991; MSF; MLL septin-like fusion protein
UniProt Entry Name
SEPT9_HUMAN
NCBI Protein Information
septin-9; septin D1; Ov/Br septin; ovarian/breast septin; MLL septin-like fusion protein MSF-A

NCBI Summary for SEPT9

This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]
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UniProt Comments for SEPT9

SEPT9: a member of a family of novel GTP binding proteins that have been implicated in cytokinesis and exocytosis. This family include the cell division control proteins CDC3, CDC10, CDC11. Required for the completion of cytokinesis and suggest a role that is distinct from that of Nedd5.

Protein type: Hydrolase; Cytoskeletal; Cell cycle regulation

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: microtubule; perinuclear region of cytoplasm; cytoplasm; stress fiber; actin cytoskeleton

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: cell division; protein heterooligomerization; metabolic process; cell cycle

Disease: Amyotrophy, Hereditary Neuralgic
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Research Articles on SEPT9

1. The identification of a SEPT9 mutation in a neonate with respiratory distress due to vocal cord paralysis expands the differential diagnosis in these patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SEPT9 antibody

 Products by Pathway  Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram

Diseases associated with anti-SEPT9 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >58 publications with SEPT9 and Neoplasms
 Nervous System Diseases Antibodies  >20 publications with SEPT9 and Nervous System Diseases
 Brachial Plexus Neuritis Antibodies  >15 publications with SEPT9 and Brachial Plexus Neuritis
 Leukemia, Myeloid, Acute Antibodies  >14 publications with SEPT9 and Leukemia, Myeloid, Acute
 Carcinoma Antibodies  >11 publications with SEPT9 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >9 publications with SEPT9 and Cell Transformation, Neoplastic
 Ovarian Neoplasms Antibodies  >6 publications with SEPT9 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >4 publications with SEPT9 and Disease Models, Animal
 Precancerous Conditions Antibodies  >3 publications with SEPT9 and Precancerous Conditions
 Neoplasms, Experimental Antibodies  >3 publications with SEPT9 and Neoplasms, Experimental

Organs/Tissues associated with anti-SEPT9 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >20 publications with SEPT9 and Blood
 Nerve Antibodies  >12 publications with SEPT9 and Nerve
 Prostate Antibodies  >9 publications with SEPT9 and Prostate
 Muscle Antibodies  >6 publications with SEPT9 and Muscle
 Kidney Antibodies  >6 publications with SEPT9 and Kidney
 Embryonic Tissue Antibodies  >4 publications with SEPT9 and Embryonic Tissue
 Brain Antibodies  >4 publications with SEPT9 and Brain
 Mammary Gland Antibodies  >3 publications with SEPT9 and Mammary Gland
 Vascular Antibodies  >3 publications with SEPT9 and Vascular
 Liver Antibodies  >3 publications with SEPT9 and Liver
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