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DPYSL5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6013319

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DPYSL5, Monoclonal Antibody
Full Product Name
DPYSL5 (Dihydropyrimidinase-related Protein 5, DRP-5, CRMP3-associated Molecule, CRAM, Collapsin Response Mediator Protein 5, CRMP-5, UNC33-like Phosphoprotein 6, ULIP-6, CRMP5, ULIP6)
Product Gene Name
Product Synonym Names
Anti -DPYSL5 (Dihydropyrimidinase-related Protein 5, DRP-5, CRMP3-associated Molecule, CRAM, Collapsin Response Mediator Protein 5, CRMP-5, UNC33-like Phosphoprotein 6, ULIP-6, CRMP5, ULIP6)
Immunogen Sequence
SFPDTVYKKL VQREKTLKVR GVDRTPYLGD VAVVVHPGKK EMGTPLADTP TRPVTRHGGM RDLHESSFSL SGSQIDDHVP KRASARILAP PGGRSSGIW
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2G4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human DPYSL5.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
61,421 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (27070969..27173219). Location: 2p23.3
OMIM
608383
3D Structure
ModBase 3D Structure for Q9BPU6
Immunogen
Partial recombinant corresponding to aa466-565 from human DPYSL5 (NP_064519) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-DPYSL5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-DPYSL5 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-DPYSL5 antibody

Western Blot detection against Immunogen (37kD).
Mouse Anti-DPYSL5 Monoclonal Antibody – Cat# MBS6013319

Western Blot (WB) of anti-DPYSL5 antibody

Western Blot analysis of DPYSL5 expression in transfected 293T cell line by DPYSL5 monoclonal antibody.|Lane 1: DPYSL5 transfected lysate (61.4kD).|Lane 2: Non-transfected lysate.
Mouse Anti-DPYSL5 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6013319

Testing Data of anti-DPYSL5 antibody

Detection limit for recombinant GST tagged DPYSL5 is 0.1ng/ml as a capture antibody.
Mouse Anti-DPYSL5 Monoclonal Antibody, Testing Data – Cat# MBS6013319

Other Notes

Small volumes of anti-DPYSL5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DPYSL5 purchase

MBS6013319 is an antibody targeting DPYSL5. Also known as DPYSL5 (Dihydropyrimidinase-related Protein 5, DRP-5, CRMP3-associated Molecule, CRAM, Collapsin Response Mediator Protein 5, CRMP-5, UNC33-like Phosphoprotein 6, ULIP-6, CRMP5, ULIP6). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DPYSL5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
DPYSL5 protein
NCBI Official Synonym Full Names
dihydropyrimidinase-like 5
NCBI Official Symbol
DPYSL5
NCBI Official Synonym Symbols
CRAM; CRMP5; Ulip6; CRMP-5
UniProt Protein Name
Dihydropyrimidinase-related protein 5
UniProt Synonym Protein Names
CRMP3-associated molecule; CRAM; Collapsin response mediator protein 5; CRMP-5; UNC33-like phosphoprotein 6
UniProt Gene Name
DPYSL5
UniProt Synonym Gene Names
CRMP5; ULIP6; DRP-5; CRAM; CRMP-5; ULIP-6
UniProt Entry Name
DPYL5_HUMAN
NCBI Protein Information
dihydropyrimidinase-related protein 5; DRP-5; ULIP-6; CRMP3-associated molecule; UNC33-like phosphoprotein 6; collapsin response mediator protein 5; collapsin response mediator protein-5

NCBI Summary for DPYSL5

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
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UniProt Comments for DPYSL5

CRMP-5: May have a function in neuronal differentiation and/or axon growth. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cell soma; dendrite; cytosol

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Biological Process: axon guidance; nervous system development; signal transduction; pyrimidine base catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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