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ANLN Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6013325

Anillin is an actin-binding protein that can bind septins and is a component of the cytokinetic ring. Anillin is expressed ubiquitously but with variable levels of expression, being highest in the central nervous system. Anillin is overexpressed in diverse… More details

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Product Overview

Online Datasheet in PDF
Product Name
ANLN, Polyclonal Antibody
Full Product Name
ANLN (Actin-binding Protein Anillin, DKFZp779A055, Scraps, Scra)
Product Gene Name
Product Synonym Names
Anti -ANLN (Actin-binding Protein Anillin, DKFZp779A055, Scraps, Scra)
Immunogen Sequence
MQELNNEINM QQTVIYQASQ ALNCCVDEEH GKGSLEEAEA ERLLLIATGK RTLLIDELNK LKNEGPQRKN KASPQSEFMP SKGSVTLSEI RLPLKADFVC STVQKPDAAN YYYLIILKAG AENMVATPLA STSNSLNGDA LTFTTTFTLQ DVSNDFEINI EVYSLVQKKD PSGLDKKKKT SKSKAITPKR LLTSITTKSN IHSSVMASPG GLSAVRTSNF ALVGSYTLSL SSVGNTKFVL DKVPFLSSLE GHIYLKIKCQ VNSSVEERGF LTIFEDVSGF GAWHRRWCVL SGNCISYWTY PDDEKRKNPI GRINLANCTS RQIEPANREF CARRNTFELI TVRPQREDDR ETLVSQCRDT LCVTKNWLSA DTKEERDLWM QKLNQVLVDI RLWQPDACYK PIGKP
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ANLN.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
124,199 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (36429415..36493400). Location: 7p15-p14
3D Structure
ModBase 3D Structure for Q9NQW6
Immunogen
Full length human ANLN, aa-405 (AAH34692.1).

Product Categories/Family for anti-ANLN antibody

Applications Tested/Suitable for anti-ANLN antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ANLN antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-ANLN antibody

Western Blot analysis of ANLN expression in transfected 293T cell line by ANLN polyclonal antibody. Lane 1: ANLN transfected lysate (44.55kD). Lane 2: Non-transfected lysate.
Mouse Anti-ANLN Polyclonal Antibody – Cat# MBS6013325

Immunofluorescence (IF) of anti-ANLN antibody

Immunofluorescence of purified antibody to ANLN on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-ANLN Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6013325

Other Notes

Small volumes of anti-ANLN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANLN purchase

MBS6013325 is an antibody targeting ANLN. Also known as ANLN (Actin-binding Protein Anillin, DKFZp779A055, Scraps, Scra). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ANLN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
actin-binding protein anillin isoform 3
NCBI Official Synonym Full Names
anillin, actin binding protein
NCBI Official Symbol
ANLN
NCBI Official Synonym Symbols
scra; Scraps
UniProt Protein Name
Actin-binding protein anillin
Protein Family
UniProt Gene Name
ANLN
UniProt Entry Name
ANLN_HUMAN
NCBI Protein Information
actin-binding protein anillin

NCBI Summary for ANLN

This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
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UniProt Comments for ANLN

anillin: an actin binding protein that interacts with cleavage furrow proteins such as septins and may play a role in cytokinesis.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 7p15-p14

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; contractile ring; actin cytoskeleton

Molecular Function: actin binding

Biological Process: mitosis; cytokinesis after mitosis; regulation of exit from mitosis; septin ring assembly; hemopoietic progenitor cell differentiation

Disease: Focal Segmental Glomerulosclerosis 8
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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