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Thymidine Phosphorylase (TYMP) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601382

Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP; EC number 2.4.2.4) or gliostatin. Human TP is 482 aa (mature chain 11-482 aa; chromosome 22q13.32) dimeric protein. In the presence of inorganic orthophosphate, it… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Thymidine Phosphorylase (Tymp), Monoclonal Antibody
Full Product Name
Anti - Thymidine Phosphorylase (TYMP, ECGF1, Gliostatin, hPD-ECGF, MNGIE, PDECGF, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase, TP)
Product Gene Name
Product Synonym Names
Thymidine Phosphorylase (TYMP, ECGF1, Gliostatin, hPD-ECGF, MNGIE, PDECGF, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase, TP)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7C49
Host
Host: Mouse
Source: Human
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, before the addition of glycerol to 40%.
Purity/Purification
Purified by immunoaffinity chromatography.
Concentration
~1mg/ml (lot specific)
Specificity
Recognizes human, mouse and rat TP.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
49,336 Da
Chromosome Location
Chromosome: 15; NC_000081.5 (89202362..89207467, complement). Location: 15 F1; 15 51.6 cM
3D Structure
ModBase 3D Structure for Q99N42
Immunogen
Purified human recombinant TP protein

Product Categories/Family for anti-Tymp antibody

Applications Tested/Suitable for anti-Tymp antibody
Western Blot
Application Notes for anti-Tymp antibody
Suitable for use in Western Blot. Other applications not tested.
Dilution: Western Blot: 1-5ug/ml; Users must optimize antibody dilution depending upon the nature of samples and other technical conditions. TP is ~ 55kD. HUVEC cells or breast carcinoma or other tumor cells cab be used as positive controls.
Optimal dilutions to be determined by the researcher.

Product References and Citations for anti-Tymp antibody

• 1. ishikawa F et al (1989) Nature 338, 557; Koukourakis MI et al (1997) 75, 477; Asai K et al (1992) JBC 267; 20311; Usuli K et al (1992) BBRC 184, 1311;

Other Notes

Small volumes of anti-Tymp antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tymp purchase

MBS601382 is an antibody targeting Tymp. Also known as Anti - Thymidine Phosphorylase (TYMP, ECGF1, Gliostatin, hPD-ECGF, MNGIE, PDECGF, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase, TP). Reactive in Human, Mouse, Rat. Host: Mouse
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for Tymp. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thymidine phosphorylase
NCBI Official Synonym Full Names
thymidine phosphorylase
NCBI Official Symbol
Tymp
NCBI Official Synonym Symbols
Ecgf1; PDECGF; Pdgfec; PD-ECGF; 2900072D10Rik
UniProt Protein Name
Thymidine phosphorylase
UniProt Synonym Protein Names
TdRPase
UniProt Gene Name
Tymp
UniProt Synonym Gene Names
Ecgf1
UniProt Entry Name
TYPH_MOUSE
NCBI Protein Information
thymidine phosphorylase; TP; tdRPase; gliostatin; platelet derived growth factor, endothelial cell; endothelial cell growth factor 1 (platelet-derived)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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