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Muscleblind-Like 1 (MBNL1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601399

Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the 3' UTR of… More details

$1055 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Muscleblind-like 1 (MBNL1), Monoclonal Antibody
Full Product Name
Muscleblind-like 1 (MBNL1, EXP35, EXP40, EXP42, Muscleblind-like, MBNL, MBNL Protein, Muscleblind 41kD Isoform, Triplet Expansion RNA Binding Protein, DKFZp686P06174, EXP, EXP35, EXP40, EXP42, KIAA0428)
Product Gene Name
Product Synonym Names
Anti -Muscleblind-like 1 (MBNL1, EXP35, EXP40, EXP42, Muscleblind-like, MBNL, MBNL Protein, Muscleblind 41kD Isoform, Triplet Expansion RNA Binding Protein, DKFZp686P06174, EXP, EXP35, EXP40, EXP42, KIAA0428)
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
8L845
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
This antibody is specific for MBNL 1p protein. Species Crossreactivity: This antibody works in human samples
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50%glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
39,670 Da
Chromosome Location
Chromosome: 9; NC_006096.3 (22845433..22874966, complement). Location: chromosome: 9
3D Structure
ModBase 3D Structure for Q5ZKW9
Immunogen
Fusion muscleblind-like1p/p60 human protein. Epitope: Amino acids 116-182.
Cellular Localization
Nuclear
Applications Tested/Suitable for anti-MBNL1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-MBNL1 antibody
Suitable for use in Immunofluorescence and Western Blot.

Other Notes

Small volumes of anti-MBNL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MBNL1 purchase

MBS601399 is an antibody targeting MBNL1. Also known as Muscleblind-like 1 (MBNL1, EXP35, EXP40, EXP42, Muscleblind-like, MBNL, MBNL Protein, Muscleblind 41kD Isoform, Triplet Expansion RNA Binding Protein, DKFZp686P06174, EXP, EXP35, EXP40, EXP42, KIAA0428). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MBNL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
muscleblind-like protein 1 isoform 5
NCBI Official Synonym Full Names
muscleblind-like (Drosophila)
NCBI Official Symbol
MBNL1
UniProt Protein Name
Muscleblind-like protein 1
UniProt Gene Name
MBNL1
UniProt Entry Name
MBNL1_CHICK
NCBI Protein Information
muscleblind-like protein 1; muscleblind-like 1

UniProt Comments for MBNL1

Function: Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA

By similarity.

Subcellular location: Nucleus

By similarity. Cytoplasm

By similarity. Cytoplasmic granule

By similarity.

Sequence similarities: Belongs to the muscleblind family.Contains 4 C3H1-type zinc fingers.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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