Prostaglandin D Synthase, Hematopoietic Form Antibody – Rat Monoclonal

Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin-type enzyme (-trace) and the hematopoietic enzyme. Lipocalin-type PGD synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as beta-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic PGD synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione S-transferases and is approximately 23kD in size.

Hematopoetic prostaglandin D synthase: an ESR1-dependent oviductal epithelial cell synthase. Phillip J. Bridges, Myoungkun Jeoung, Sarah Shim, Ji Yeon Park, Jae Eun Lee, Lindsay A. Sapsford, Kourtney Trudgen, Chemyong Ko, Myung Chan Gye, and Misung Jo (2012)

Small volumes of anti-Prostaglandin D Synthase, Hematopoietic form antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS601438 is an antibody targeting Prostaglandin D Synthase, Hematopoietic form. Also known as Prostaglandin D Synthase, Hematopoietic form (PGD Synthase). Reactive in Human, Mouse. Host: Rat.