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Macrophage, Monocyte Chemotactic Protein-3 (CCL7) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601556

MBS601556 is an antibody targeting Ccl7. Also known as Macrophage, Monocyte Chemotactic Protein-3 (MCP-3, CCL7, MARC). Reactive in Human. Host: Mouse. More details

$845 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Macrophage, Monocyte Chemotactic Protein-3 (Ccl7), Monoclonal Antibody
Full Product Name
Macrophage, Monocyte Chemotactic Protein-3 (MCP-3, CCL7, MARC)
Product Gene Name
Product Synonym Names
Anti -Macrophage, Monocyte Chemotactic Protein-3 (MCP-3, CCL7, MARC)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2619
Host
Mouse
Species Reactivity
Human
Form/Format
Purified IgG - lyophilized in PBS. Reconstitute with 0.5ml distilled water.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Specifically recognizes Human MCP-3, also known as CCL7. No crossreactivity is observed with MCP-1, MCP-2 or other structurally related chemokines.
Preparation and Storage
-20 degree C
Molecular Weight
10,999 Da
Chromosome Location
Chromosome: 11; NC_000077.5 (81859214..81861027). Location: 11 C; 11 46.5 cM
3D Structure
ModBase 3D Structure for Q03366
Immunogen
Recombinant human MCP-3 (Macrophage Chemoattractant Protein-3).
Fusion Partners
Spleen cells from immunized C3H/HeJ mice were fused with cells of a mouse myeloma cell line
Applications Tested/Suitable for anti-Ccl7 antibody
Immunohistochemistry (IHC), Neutralization
Application Notes for anti-Ccl7 antibody
ELISA: 1:1000, Chemotaxis neutralization assays: 1:1000, Optimal working dilutions to be determined by researcher.

Other Notes

Small volumes of anti-Ccl7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
monocyte chemotactic protein-3
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 7
NCBI Official Symbol
Ccl7
NCBI Official Synonym Symbols
fic; marc; mcp3; MCP-3; Scya7
UniProt Protein Name
C-C motif chemokine 7
UniProt Synonym Protein Names
Intercrine/chemokine MARC; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; Protein FIC; Small-inducible cytokine A7
Protein Family
UniProt Gene Name
Ccl7
UniProt Synonym Gene Names
Fic; Mcp3; Scya7
UniProt Entry Name
CCL7_MOUSE
NCBI Protein Information
C-C motif chemokine 7; OTTMUSP00000000787; RANTES/sis homolog; intercrine/chemokine MARC; small inducible cytokine A7; small-inducible cytokine A7; monocyte chemotactic protein 3; monocyte chemoattractant protein 3

UniProt Comments for Ccl7

CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR2 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: immune response; chemotaxis; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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