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GNA13 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601801

MBS601801 is an antibody targeting GNA13. Also known as GNA13 (Guanine Nucleotide Binding Protein (G protein) alpha 13, G13, MGC46138). Reactive in Human. Host: Mouse. More details

$560 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNA13, Monoclonal Antibody
Full Product Name
GNA13 (Guanine Nucleotide Binding Protein (G protein) alpha 13, G13, MGC46138)
Product Gene Name
anti-GNA13 antibody
Product Synonym Names
Anti -GNA13 (Guanine Nucleotide Binding Protein (G protein) alpha 13, G13, MGC46138)
Immunogen Sequence
MADFLPSRSV LSVCFPGCLL TSGEAEQQRK SKEIDKCLSR EKTYVKRLVK ILLLGAGESG KSTFLKQMRI IHGQDFDQRA REEFRPTIYS NVIKGMRVLV DAREKLHIPW GDNSNQQHGD KMMSFDTRAP MAAQGMVETR VFLQYLPAIR ALWADSGIQN AYDRRREFQL GESVKYFLDN LDKLGEPDYI PSQQDILLAR RPTKGIHEYD FEIKNVPFKM VDVGGQRSER KRWFECFDSV TSILFLVSSS EFDQV
Clonality
Monoclonal
Clone Number
5E90
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human GNA13.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
44,050 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (63005407..63052920, complement). Location: 17q24.3
OMIM
604406
3D Structure
ModBase 3D Structure for Q14344
Immunogen
Human GNA13 (aa1-378) with GST Tag. Molecular Weight: 67.21kD (with tag)

Product Categories/Family for anti-GNA13 antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-GNA13 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-GNA13 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:250
Western Blot: 1:250

Other Notes

Small volumes of anti-GNA13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GNA13. It may not necessarily be applicable to this product.

NCBI GI #
24111250
NCBI GeneID
10672
NCBI Accession #
NP_006563.2
UniProt Primary Accession #
Q14344
UniProt Secondary Accession #
Q8TD70; B2R977
UniProt Related Accession #
Q14344
GenBank Nucleotide #
NM_006572.4
NCBI Official Full Name
guanine nucleotide-binding protein subunit alpha-13
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), alpha 13
NCBI Official Symbol
GNA13
NCBI Official Synonym Symbols
G13; MGC46138
UniProt Protein Name
Guanine nucleotide-binding protein subunit alpha-13
Protein Family
Guanine nucleotide-binding protein
UniProt Gene Name
GNA13
UniProt Entry Name
GNA13_HUMAN
NCBI Protein Information
guanine nucleotide-binding protein subunit alpha-13; g alpha-13; G-protein subunit alpha-13

UniProt Comments for GNA13

G-alpha 13: a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Activates Rho. Protein kinase A blocks Rho activation by phosphorylation of G-alpha(13). Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes.

Protein type: G protein, heterotrimeric alpha G(12); G protein; G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: focal adhesion; membrane; brush border membrane; melanosome; plasma membrane; heterotrimeric G-protein complex; nucleus

Molecular Function: GTPase activity; protein binding; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; type 1 angiotensin receptor binding; D5 dopamine receptor binding

Biological Process: phospholipase D activation; platelet activation; in utero embryonic development; metabolic process; signal transduction; G-protein signaling, adenylate cyclase activating pathway; regulation of cell migration; Rho protein signal transduction; patterning of blood vessels; regulation of cell shape; elevation of cytosolic calcium ion concentration; cell motility; cell differentiation; blood coagulation
Show more

Research Articles on GNA13

1. Galpha(12/13) regulate AP-1-dependent CYR61 induction in vascular smooth muscle, promoting migration, and they are upregulated with CYR61 in arteriosclerotic lesions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GNA13 antibody

 Reference Product  PubMed Publications
 RGS16 antibody  >1 publications with GNA13 and RGS16
 GNA12 antibody  >1 publications with GNA13 and GNA12
 AKAP3 antibody  >1 publications with GNA13 and AKAP3

Pathways associated with anti-GNA13 antibody

 Products by Pathway  Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Formation Of Platelet Plug Pathway antibodies  Formation Of Platelet Plug Pathway Diagram
 G Protein Signaling Pathways antibodies  G Protein Signaling Pathways Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 G13 Signaling Pathway antibodies  G13 Signaling Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 LPA Receptor Mediated Events Pathway antibodies  LPA Receptor Mediated Events Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram

Diseases associated with anti-GNA13 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with GNA13 and Disease Models, Animal
 Neoplasms Antibodies  >1 publications with GNA13 and Neoplasms

Organs/Tissues associated with anti-GNA13 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with GNA13 and Testis
 Embryonic Tissue Antibodies  >1 publications with GNA13 and Embryonic Tissue
 Placenta Antibodies  >1 publications with GNA13 and Placenta
 Brain Antibodies  >1 publications with GNA13 and Brain
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