• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

C-Erbb2, P185 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602071

c-erbB-2 is a membrane-associated oncoprotein having considerable sequence homology to EGFR. C-erbB-2 is the second member of the EGF receptor tyrosine kinase family of growth factor receptors. Overexpression of c-erbB-2/HER-2 is reportedly a marker of poor… More details

$970 / 0.5 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
c-erbB2, p185, Monoclonal Antibody
Full Product Name
c-erbB2, p185 (HER2, neu Receptor)
Product Synonym Names
Anti -c-erbB2, p185 (HER2, neu Receptor)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
0.N.210
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide. Also available without BSA and azide. See C0015-10X.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human c-erbB-2 at 185kD. Species Crossreactivity: Does not crossreact with mouse or rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
RAC311 cells transfected with SV40-neu construct, expressing human neu protein. Cellular Localization: Cell membrane.
Positive Control
SKBR-3, LS174T, MAD109 or T47D, and breast carcinomas

Product Categories/Family for anti-c-erbB2, p185 antibody

Antibodies; Abs to Oncoproteins
Applications Tested/Suitable for anti-c-erbB2, p185 antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-c-erbB2, p185 antibody
Suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation and Immunohistochemistry. Inhibits colony formation and partially inhibits tyrosine kinase activity.
Dilution: Immunoprecipitation: Use Protein G at 2ug/mg protein lysate.
Immunohistochemistry: Frozen only.
Inhibition: C0015-10X (Order antibody without sodium azide).

Testing Data of anti-c-erbB2, p185 antibody

Human colon cancer cells stained with MBS602071 using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of cultured cells.
Mouse Anti-C-Erbb2, P185 Monoclonal Antibody – Cat# MBS602071

Other Notes

Small volumes of anti-c-erbB2, p185 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for c-erbB2, p185 purchase

MBS602071 is an antibody targeting c-erbB2, p185. Also known as c-erbB2, p185 (HER2, neu Receptor). Reactive in Human. Host: Mouse.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000