Mouse Anti-PTPRZ1 Monoclonal Antibody – Cat# MBS602167

Immunohistochemistry: Phosphacan (Receptor Tyrosine Phosphatase beta) MBS602167 staining of adult rat hippocampus. Photo shows dentate gyrus.

Phosphacan (PTPRZ1) Antibody – Mouse Monoclonal

Name: PTPRZ1 Antibody; Monoclonal; Mouse; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS602167
Price: 1015 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602167

Phosphacan is a soluble nervous tissue-specific proteoglycan that is thought to regulate axonal outgrowth. It is synthesized by glia. It inds to neurons and to the neural cell adhesion molecules tenascin, N-CAM or NG-CAM. It does not bind to laminin and… More details

$1015 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Phosphacan (PTPRZ1), Monoclonal Antibody

Full Product Name

Phosphacan (Receptor Tyrosine Phosphatase beta)

Product Gene Name

anti-PTPRZ1 antibody

Product Synonym Names

Anti -Phosphacan (Receptor Tyrosine Phosphatase beta)

Clonality

Monoclonal

Isotype

IgM

Clone Number

2Q134

Host

Mouse

Species Reactivity

Rat

Form/Format

Supplied as a liquid. No preservatives added.

Purity/Purification

Ascites
Ascites

Specificity

Recognizes the core protein of rat Phosphacan (Receptor Tyrosine Phosphatase Beta).

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

254,587 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (121513159..121702090). Location: 7q31.3

OMIM

176891

3D Structure

ModBase 3D Structure for P23471

Immunogen

Phosphacan

Positive Control

Embryonic or early post-natal rat brain.

Product Categories/Family for anti-PTPRZ1 antibody

Antibodies; Abs to Receptors

Applications Tested/Suitable for anti-PTPRZ1 antibody

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Application Notes for anti-PTPRZ1 antibody

Suitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation.
Dilution: Immunocytochemistry: 1:10
Immunohistochemistry (4% Paraformaldehyde fixed): 1:1000 Western Blot: Recognizes bands at 250, 190 and 180kD from embryonic rat brain extracts.

Other Notes

Small volumes of anti-PTPRZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPRZ1 purchase

MBS602167 is an antibody targeting PTPRZ1. Also known as Phosphacan (Receptor Tyrosine Phosphatase beta). Reactive in Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRZ1. It may not necessarily be applicable to this product.

NCBI GI #

530386271

NCBI GeneID

5803

NCBI Accession #

XP_005250576.1

UniProt Primary Accession #

P23471

UniProt Secondary Accession #

O76043; Q9UDR6; A4D0W5

UniProt Related Accession #

P23471

GenBank Nucleotide #

XM_005250519.1

NCBI Official Full Name

receptor-type tyrosine-protein phosphatase zeta isoform X1

NCBI Official Synonym Full Names

protein tyrosine phosphatase, receptor-type, Z polypeptide 1

NCBI Official Symbol

PTPRZ1

NCBI Official Synonym Symbols

PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2

UniProt Protein Name

Receptor-type tyrosine-protein phosphatase zeta

UniProt Synonym Protein Names

Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2

Protein Family

Receptor-type tyrosine-protein phosphatase

UniProt Gene Name

PTPRZ1

UniProt Synonym Gene Names

HTPZP2; PTPRZ; PTPRZ2; PTPZ; R-PTP-zeta

UniProt Entry Name

PTPRZ_HUMAN

NCBI Protein Information

receptor-type tyrosine-protein phosphatase zeta; receptor-type tyrosine phosphatase beta/zeta; protein-tyrosine phosphatase receptor type Z polypeptide 2; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1

NCBI Summary for PTPRZ1

This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

UniProt Comments for PTPRZ1

PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; Receptor protein phosphatase, tyrosine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q31.3

Cellular Component: proteinaceous extracellular matrix; integral to plasma membrane

Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity

Biological Process: learning and/or memory; central nervous system development; axonogenesis; oligodendrocyte differentiation; hemopoietic progenitor cell differentiation; protein amino acid dephosphorylation

Disease: Helicobacter Pylori Infection, Susceptibility To

Research Articles on PTPRZ1

1. PTPRZ1 was highly expressed in human neuroendocrine tumor tissues and PTPRZ1 is an oncogenic tyrosine phosphatase in small-cell lung carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTPRZ1 antibody

Reference Product	PubMed Publications
NCAN antibody	>32 publications with PTPRZ1 and NCAN
PTN antibody	>18 publications with PTPRZ1 and PTN
ERBB4 antibody	>4 publications with PTPRZ1 and ERBB4
GIT1 antibody	>4 publications with PTPRZ1 and GIT1
EGF antibody	>2 publications with PTPRZ1 and EGF
CNTN1 antibody	>2 publications with PTPRZ1 and CNTN1
TNC antibody	>1 publications with PTPRZ1 and TNC

Pathways associated with anti-PTPRZ1 antibody

Products by Pathway	Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Spinal Cord Injury Pathway antibodies	Spinal Cord Injury Pathway Diagram

Diseases associated with anti-PTPRZ1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>39 publications with PTPRZ1 and Neoplasms
Nervous System Diseases Antibodies	>38 publications with PTPRZ1 and Nervous System Diseases
Brain Diseases Antibodies	>29 publications with PTPRZ1 and Brain Diseases
Lymphoma Antibodies	>6 publications with PTPRZ1 and Lymphoma
Nerve Degeneration Antibodies	>5 publications with PTPRZ1 and Nerve Degeneration
Inflammation Antibodies	>4 publications with PTPRZ1 and Inflammation
Vascular Diseases Antibodies	>4 publications with PTPRZ1 and Vascular Diseases
Breast Neoplasms Antibodies	>2 publications with PTPRZ1 and Breast Neoplasms
Lung Neoplasms Antibodies	>2 publications with PTPRZ1 and Lung Neoplasms
Kidney Diseases Antibodies	>2 publications with PTPRZ1 and Kidney Diseases

Organs/Tissues associated with anti-PTPRZ1 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>114 publications with PTPRZ1 and Nerve
Brain Antibodies	>95 publications with PTPRZ1 and Brain
Embryonic Tissue Antibodies	>27 publications with PTPRZ1 and Embryonic Tissue
Connective Tissue Antibodies	>4 publications with PTPRZ1 and Connective Tissue
Ganglia Antibodies	>4 publications with PTPRZ1 and Ganglia
Eye Antibodies	>4 publications with PTPRZ1 and Eye
Lung Antibodies	>2 publications with PTPRZ1 and Lung
Kidney Antibodies	>2 publications with PTPRZ1 and Kidney
Muscle Antibodies	>2 publications with PTPRZ1 and Muscle
Testis Antibodies	>1 publications with PTPRZ1 and Testis