CD44V10 Antibody – Mouse Monoclonal

CD44 is the receptor for hyaluronan. The interaction between CD44 and hyaluronan may mediate binding of cells to basement membranes. Several CD44 isoforms or variants arise from alternative splicing of mRNA transcribed from a single gene located on chromosome 11. The alternatively spliced mRNA's are translated into a family of protein isoforms which contain inserts in their cytoplasmic domains of varying lengths. Most cell types express the standard CD44, while the expression of the isoforms resulting from the alternative splicing is of limited distribution. CD44 isoforms resulting from alternative splicing have been detected in many human tumors; therefore, the identification of CD44 isoforms has utility in cancer studies.

Small volumes of anti-CD44V10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS602295 is an antibody targeting CD44V10. Also known as CD44V10 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1). Reactive in Human. Host: Mouse.