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ADNP Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602332

MBS602332 is an antibody targeting ADNP. Also known as ADNP (Activity Dependent Neuroprotective Protein). Reactive in Human, Mouse, Rat. Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADNP, Monoclonal Antibody
Full Product Name
ADNP (Activity Dependent Neuroprotective Protein)
Product Gene Name
Product Synonym Names
Anti -ADNP (Activity Dependent Neuroprotective Protein)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C9
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human ADNP.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
123,447 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (49506883..49547527, complement). Location: 20q13.13
3D Structure
ModBase 3D Structure for Q6DHZ8
Immunogen
Partial sequence of recombinant full-length protein to human ADNP
Applications Tested/Suitable for anti-ADNP antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-ADNP antibody
Suitable for use in Flow Cytometry, ELISA and Western Blot.

Western Blot (WB) of anti-ADNP antibody

Western Blot of recombinant using|MBS602332
Mouse Anti-ADNP Monoclonal Antibody – Cat# MBS602332

Western Blot (WB) of anti-ADNP antibody

Detection of ADNP by Western blot using A0901-01Con whole cell lysate from human HEK293 (H, 25ug) , mouse NIH3T3 (M, 25ug) and rat F2408 (R, 25ug) cells. Predicted molecular weight: 123kD.
Mouse Anti-ADNP Monoclonal Antibody, Western Blot (WB) – Cat# MBS602332

Other Notes

Small volumes of anti-ADNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADNP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
activity-dependent neuroprotector homeobox protein
NCBI Official Synonym Full Names
activity-dependent neuroprotector homeobox
NCBI Official Symbol
ADNP
NCBI Official Synonym Symbols
ADNP1; KIAA0784
UniProt Protein Name
Activity-dependent neuroprotector homeobox
UniProt Gene Name
ADNP
UniProt Entry Name
Q6DHZ8_HUMAN
NCBI Protein Information
activity-dependent neuroprotector homeobox protein; ADNP homeobox 1; OTTHUMP00000031275; OTTHUMP00000031276; OTTHUMP00000165329; OTTHUMP00000229415; activity-dependent neuroprotective protein

NCBI Summary for ADNP

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
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UniProt Comments for ADNP

ADNP: Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.

Protein type: DNA-binding; C2H2-type zinc finger protein; Apoptosis

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: extracellular space; nucleus

Molecular Function: protein binding; DNA binding; metal ion binding; chromatin binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of neuron apoptosis

Disease: Mental Retardation, Autosomal Dominant 28
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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