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BCAS3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602743

MBS602743 is an antibody targeting BCAS3. Also known as BCAS3 (Breast Carcinoma Amplified Sequence 3, FLJ20128, GAOB1, MAAB, MGC4973). Reactive in Human, Mouse, Rat. Host: Mouse. More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BCAS3, Monoclonal Antibody
Full Product Name
BCAS3 (Breast Carcinoma Amplified Sequence 3, FLJ20128, GAOB1, MAAB, MGC4973)
Product Gene Name
anti-BCAS3 antibody
Product Synonym Names
Anti -BCAS3 (Breast Carcinoma Amplified Sequence 3, FLJ20128, GAOB1, MAAB, MGC4973)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C30
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human BCAS3.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
101,237 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (58755172..59470199). Location: 17q23
OMIM
607470
3D Structure
ModBase 3D Structure for Q17RM0
Immunogen
Partial sequence of recombinant full-length protein to human BCAS3

Product Categories/Family for anti-BCAS3 antibody

Antibodies; Abs to Cancer Markers
Applications Tested/Suitable for anti-BCAS3 antibody
Western Blot (WB)
Application Notes for anti-BCAS3 antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

Western Blot (WB) of anti-BCAS3 antibody

Western Blot anaylsis of immunized recombinant protein using MBS602743
Mouse Anti-BCAS3 Monoclonal Antibody – Cat# MBS602743

Western Blot (WB) of anti-BCAS3 antibody

Detection of BCAS3 by Western blot. Samples: Whole cell lysate from human HeLa (H, 50ug) , mouse NIH3T3 (M, 50 ug) and rat F2408 (R, 50ug) cells. Predicted molecular weight: 99 kD
Mouse Anti-BCAS3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS602743

Testing Data of anti-BCAS3 antibody

HeLa cells were fixed in 2% paraformaldehyde/PBS and then permeabilized in 90% methanol. Cells were stained with MBS602743(shaded) or isotype control (unshaded) followed by Alexa Fluor® 488- conjugated goat anti-mouse IgG.
Mouse Anti-BCAS3 Monoclonal Antibody, Testing Data – Cat# MBS602743

Immunostaining (IS) of anti-BCAS3 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with MBS602743
Mouse Anti-BCAS3 Monoclonal Antibody, Immunostaining (IS) – Cat# MBS602743

Other Notes

Small volumes of anti-BCAS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BCAS3. It may not necessarily be applicable to this product.

NCBI GI #
153218631
NCBI GeneID
54828
NCBI Accession #
NP_001092902.1
UniProt Primary Accession #
Q17RM0
UniProt Secondary Accession #
Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55; Q9BVF0; Q9H957; Q9H9Y9; Q9NXP4
UniProt Related Accession #
Q05D99; Q70WD9; Q9H6U6
GenBank Nucleotide #
NM_001099432.1
NCBI Official Full Name
breast carcinoma-amplified sequence 3 isoform 1
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 3
NCBI Official Symbol
BCAS3
NCBI Official Synonym Symbols
MAAB; GAOB1; MGC4973; FLJ20128; DKFZp686O1527
UniProt Protein Name
Breast carcinoma-amplified sequence 3
UniProt Synonym Protein Names
GAOB1
Protein Family
Breast carcinoma-amplified sequence
UniProt Gene Name
BCAS3
UniProt Entry Name
BCAS3_HUMAN
NCBI Protein Information
breast carcinoma-amplified sequence 3; protein Maab1; BCAS4/BCAS3 fusion; metastasis associated antigen of breast cancer; breast carcinoma amplified sequence 4/3 fusion protein

UniProt Comments for BCAS3

BCAS3: A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4. Belongs to the WD repeat BCAS3 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: intermediate filament cytoskeleton; cytoplasmic microtubule; leading edge; cytoplasm; nucleus

Molecular Function: histone acetyltransferase binding; protein binding; histone binding; beta-tubulin binding; chromatin binding; transcription factor binding; nuclear hormone receptor binding

Biological Process: vesicle-mediated transport; response to starvation; positive regulation of filopodium formation; positive regulation of catalytic activity; microtubule organizing center organization and biogenesis; transcription, DNA-dependent; negative regulation of focal adhesion formation; positive regulation of transcription from RNA polymerase II promoter; lumen formation; angiogenesis; Golgi organization and biogenesis
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Research Articles on BCAS3

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-BCAS3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >10 publications with BCAS3 and Neoplasms
 Breast Neoplasms Antibodies  >6 publications with BCAS3 and Breast Neoplasms
 Adenocarcinoma Antibodies  >1 publications with BCAS3 and Adenocarcinoma
 Esophageal Neoplasms Antibodies  >1 publications with BCAS3 and Esophageal Neoplasms

Organs/Tissues associated with anti-BCAS3 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with BCAS3 and Kidney
 Embryonic Tissue Antibodies  >1 publications with BCAS3 and Embryonic Tissue
 Brain Antibodies  >1 publications with BCAS3 and Brain
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