• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Integrin Alphav, Beta3 (ITGB3) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603136

The integrin family of cell adhesion receptors consists of a least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based on… More details

$1050 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin alphaV, beta3 (ITGB3), Monoclonal Antibody
Full Product Name
Integrin alphaV, beta3
Product Gene Name
Product Synonym Names
Anti -Integrin alphaV, beta3
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q880
Host
Mouse
Species Reactivity
Avian, Bovine, Canine, Chicken, Human, Monkey, Porcine, Rabbit
Form/Format
Supplied as a liquid in PBS, pH 7.6. No preservative added.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes the human vitronectin receptor aVb3 complex, an RGD-directed adhesion receptor. Species Crossreactivity: Avian, bovine, canine, chicken, monkey, porcine and rabbit. Not reactive with rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Chromosome Location
Chromosome: 12; NC_010454.3 (16718915..16775379, complement). Location: chromosome: 12
Immunogen
Purified adhesion receptor from the human melanoma cell line M21.

Product Categories/Family for anti-ITGB3 antibody

Applications Tested/Suitable for anti-ITGB3 antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-ITGB3 antibody
Suitable for use in Immunoprecipitation, Immunofluorescence, Flow Cytometry, Immunohistochemistry (frozen sections only), Immunocytochemistry and Blocking.
Dilution: Immunoprecipitation: Precipitates integrin alphaV beta3 complex. When resolved by SDS-PAGE under reducing conditions, bands are observed at ~130kD and ~105kD corresponding to the alphaV and beta3 subunits, respectively.
Immunofluorescence: 5-10ug/ml for staining of bFGF-treated 6um cryosections of chick chorioallantoic membrane fixed with acetone. Also effective on 4% paraformaldehyde fixed, frozen tissues and cells. Not effective for immunohistochemical staining of paraffin-embedded tissue sections.
Flow Cytometry: 1-3ug/0.5x10e6 cells in 100ul volume
Blocking: Inhibits adhesion of cells to vitronectin-coated surfaces at 10-25ug/ml

Other Notes

Small volumes of anti-ITGB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ITGB3 purchase

MBS603136 is an antibody targeting ITGB3. Also known as Integrin alphaV, beta3. Reactive in Avian, Bovine, Canine, Chicken, Human, Monkey, Porcine, Rabbit. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGB3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin beta-3
NCBI Official Symbol
ITGB3
NCBI Official Synonym Symbols
CD61
Protein Family
NCBI Protein Information
integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000