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EXOC4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603312

rSec6 is an 87kD rat homolog of yeast Sec6p, a protein involved in protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec6p is part of a high molecular weight complex which includes Sec8p and Sec15p, that associates with the… More details

$680 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
rSec6 (Exoc4), Monoclonal Antibody
Full Product Name
rSec6
Product Gene Name
Product Synonym Names
Anti -rSec6
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4E199
Host
Mouse
Species Reactivity
Bovine, Canine, Chicken, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep
Form/Format
Supplied as a liquid in PBS, pH7.2, 0.1mM PMSF, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes rSec6 at 87kD. Species Cross Reactivity: human, mouse, rat, bovine, canine, chicken, hamster, sheep, porcine, monkey and rabbit. Immunofluorescence of PC12 cells shows co-localization of rSec6 with vesicles and sites of exocytosis.
Preparation and Storage
For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
110,553 Da
Chromosome Location
Chromosome: 4; NC_005103.2 (60406942..61284294). Location: 4q22
3D Structure
ModBase 3D Structure for Q62824
Immunogen
Recombinant rat rSec6 protein.

Product Categories/Family for anti-Exoc4 antibody

Applications Tested/Suitable for anti-Exoc4 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-Exoc4 antibody
Dilution: Western Blot (ECL): 1:250.
Optimal dilutions to be determined by researcher.

Positive Controls:
Rat Brain Tissue Extract.
Mouse Brain Tissue Extract

Western Blot (WB) of anti-Exoc4 antibody

Western blot analysis of pig ESK-4 cell lysate, probed with MBS603312.
Mouse Anti-EXOC4 Monoclonal Antibody – Cat# MBS603312

Other Notes

Small volumes of anti-Exoc4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Exoc4 purchase

MBS603312 is an antibody targeting Exoc4. Also known as rSec6. Reactive in Bovine, Canine, Chicken, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Exoc4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
rsec8
NCBI Official Synonym Full Names
exocyst complex component 4
NCBI Official Symbol
Exoc4
NCBI Official Synonym Symbols
ALR; Sec8; Sec8l1
UniProt Protein Name
Exocyst complex component 4
UniProt Synonym Protein Names
Exocyst complex component Sec8
UniProt Gene Name
Exoc4
UniProt Synonym Gene Names
Sec8; Sec8l1
UniProt Entry Name
EXOC4_RAT
NCBI Protein Information
exocyst complex component 4; rSec8; SEC8-like 1; secretory protein SEC8; exocyst complex component Sec8; augmenter of liver regeneration (ALR) pseudogene

NCBI Summary for Exoc4

involved in Golgi-to-plasma membrane vesicle trafficking [RGD]

UniProt Comments for Exoc4

EXOC4: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC8 family.

Protein type: Vesicle

Cellular Component: Golgi apparatus; neuron projection; protein complex; growth cone; cell soma; membrane; postsynaptic density; cytoplasm; exocyst; synapse; dendritic shaft; myelin sheath; endosome

Molecular Function: protein binding; protein complex binding; Ral GTPase binding; protein N-terminus binding; PDZ domain binding

Biological Process: regulation of protein transport; synaptic transmission; Golgi to transport vesicle transport; establishment of cell polarity; vesicle targeting; oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; protein targeting to membrane; vesicle docking during exocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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