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FOXN3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603543

MBS603543 is an antibody targeting FOXN3. Also known as FOXN3 (Forkhead Box N3, Checkpoint Suppressor 1). Host: Mouse. More details

$610 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FOXN3, Monoclonal Antibody
Full Product Name
FOXN3 (Forkhead Box N3, Checkpoint Suppressor 1)
Product Gene Name
Product Synonym Names
Anti -FOXN3 (Forkhead Box N3, Checkpoint Suppressor 1)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C152
Host
Mouse
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Concentration
0.1mg/ml (lot specific)
Specificity
Recognizes human FOXN3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
53,835 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (89622516..90085494, complement). Location: 14q31.3
OMIM
602628
3D Structure
ModBase 3D Structure for O00409
Immunogen
Partial sequence of recombinant full-length protein to human FOXN3
Applications Tested/Suitable for anti-FOXN3 antibody
Western Blot (WB)
Application Notes for anti-FOXN3 antibody
Suitable for use in Western Blotting.
Recommended Dilution: Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of anti-FOXN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
forkhead box protein N3 isoform 1
NCBI Official Synonym Full Names
forkhead box N3
NCBI Official Symbol
FOXN3
NCBI Official Synonym Symbols
CHES1; PRO1635; C14orf116
UniProt Protein Name
Forkhead box protein N3
UniProt Synonym Protein Names
Checkpoint suppressor 1
Protein Family
UniProt Gene Name
FOXN3
UniProt Synonym Gene Names
C14orf116; CHES1
UniProt Entry Name
FOXN3_HUMAN
NCBI Protein Information
forkhead box protein N3; checkpoint suppressor 1

NCBI Summary for FOXN3

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq]
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UniProt Comments for FOXN3

FOXN3: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 14q31.3

Cellular Component: nucleus

Molecular Function: protein C-terminus binding; protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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