• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Interleukin 17e (IL25) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603719

The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17B-IL through17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the… More details

$1010 / 100 Tests +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 17E (IL25), Monoclonal Antibody
Full Product Name
Interleukin 17E (IL-17E, Cytotoxic T-lymphocyte-associated antigen 8) (APC)
Product Gene Name
Product Synonym Names
Anti -Interleukin 17E (IL-17E, Cytotoxic T-lymphocyte-associated antigen 8) (APC)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7H5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
Purity/Purification
Affinity Purified
Purified by Protein A/G affinity chromatography.
Specificity
Recognizes human Interleukin 17E.
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Molecular Weight
20,330 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (23842018..23845612). Location: 14q11.2
OMIM
605658
3D Structure
ModBase 3D Structure for Q9H293
Immunogen
E. coli-derived recombinant human Interleukin 17E (Tyr33-Gly177, Accession #Q9H293)

Product Categories/Family for anti-IL25 antibody

Applications Tested/Suitable for anti-IL25 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-IL25 antibody
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: 10ul labels 5x10e5 cells.

Testing Data of anti-IL25 antibody

Intracellular staining of PC-3 cells with MBS603719 (filled histogram) or with isotype control antibody (open histogram).
Mouse Anti-IL25 Monoclonal Antibody – Cat# MBS603719

Other Notes

Small volumes of anti-IL25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL25 purchase

MBS603719 is an antibody targeting IL25. Also known as Interleukin 17E (IL-17E, Cytotoxic T-lymphocyte-associated antigen 8) (APC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL25. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-25 isoform 2
NCBI Official Synonym Full Names
interleukin 25
NCBI Official Symbol
IL25
NCBI Official Synonym Symbols
IL17E
UniProt Protein Name
Interleukin-25
UniProt Synonym Protein Names
Interleukin-17E
Protein Family
UniProt Gene Name
IL25
UniProt Synonym Gene Names
IL17E; IL-25; IL-17E
UniProt Entry Name
IL25_HUMAN
NCBI Protein Information
interleukin-25; interleukin-17E

NCBI Summary for IL25

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Show more

UniProt Comments for IL25

IL25: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular space

Molecular Function: cytokine activity; interleukin-17E receptor binding

Biological Process: response to fungus; inflammatory response to antigenic stimulus; response to nematode; eosinophil differentiation; positive regulation of transcription from RNA polymerase II promoter
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000