Mouse Anti-TAF4B Monoclonal Antibody – Cat# MBS603989

RNA Polymerase II, TATA Box Binding Protein (TAF4B) Antibody – Mouse Monoclonal

Name: TAF4B Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS603989
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603989

TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM… More details

$685 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAF4b RNA Polymerase II, TATA Box Binding Protein, Monoclonal Antibody

Full Product Name

TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-associated Factor, 105kD (TAF4B)

Product Gene Name

anti-Taf4b antibody

Product Synonym Names

Anti -TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-associated Factor, 105kD (TAF4B)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

8C314

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-associated Factor, 105kD.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

17,824 Da

Chromosome Location

Chromosome: 18; NC_000084.5 (14941754..15058868). Location: 18 A1; 18

3D Structure

ModBase 3D Structure for Q8C0S6

Immunogen

Partial sequence of recombinant full-length protein to human TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-associated Factor, 105kD

Product Categories/Family for anti-Taf4b antibody

Antibodies; Abs to Enzymes; Polymerase

Applications Tested/Suitable for anti-Taf4b antibody

ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC)

Application Notes for anti-Taf4b antibody

Suitable for use in ELISA, Western Blot and Immunocytochemistry.

Other Notes

Small volumes of anti-Taf4b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Taf4b purchase

MBS603989 is an antibody targeting Taf4b. Also known as TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-associated Factor, 105kD (TAF4B). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Taf4b. It may not necessarily be applicable to this product.

NCBI GI #

226958537

NCBI GeneID

72504

NCBI Accession #

NP_001093919.1

UniProt Primary Accession #

Q8C0S6

UniProt Related Accession #

Q8C0S6

GenBank Nucleotide #

NM_001100449.1

NCBI Official Full Name

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

NCBI Official Synonym Full Names

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

NCBI Official Symbol

Taf4b

NCBI Official Synonym Symbols

105kDa; Taf2c2; AW987595; TAFII105; 2610524B04Rik; 4932409F03Rik

UniProt Protein Name

Putative uncharacterized protein

Protein Family

Transcription initiation factor

UniProt Gene Name

Taf4b

UniProt Entry Name

Q8C0S6_MOUSE

NCBI Protein Information

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD; TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105 kDa

UniProt Comments for Taf4b

TAF4B: Cell type-specific subunit of TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAFII105 is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Belongs to the TAF4 family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: nucleoplasm; transcription factor complex; transcription factor TFIID complex; cytoplasm; nucleolus; nucleus

Molecular Function: NF-kappaB binding; DNA binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; oogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription initiation; spermatogenesis; cell differentiation

Research Articles on Taf4b

1. Small interfering RNA knockdown of Taf4b results in decreased cell proliferation and altered osteogenic differentiation in primary mouse embryonic maxillary mesenchymal cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Taf4b antibody

Products by Pathway	Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Formation And Maturation Of MRNA Transcript Pathway antibodies	Formation And Maturation Of MRNA Transcript Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
RNA Polymerase II Pre-transcription Events Pathway antibodies	RNA Polymerase II Pre-transcription Events Pathway Diagram
RNA Polymerase II Promoter Escape Pathway antibodies	RNA Polymerase II Promoter Escape Pathway Diagram
RNA Polymerase II Transcription Pathway antibodies	RNA Polymerase II Transcription Pathway Diagram
RNA Polymerase II Transcription Initiation Pathway antibodies	RNA Polymerase II Transcription Initiation Pathway Diagram

Organs/Tissues associated with anti-Taf4b antibody

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>11 publications with Taf4b and Ovary
Testis Antibodies	>6 publications with Taf4b and Testis
Spleen Antibodies	>3 publications with Taf4b and Spleen
Brain Antibodies	>1 publications with Taf4b and Brain
Bone Marrow Antibodies	>1 publications with Taf4b and Bone Marrow
Embryonic Tissue Antibodies	>1 publications with Taf4b and Embryonic Tissue