• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Meteorin (METRN) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603999

Meteorin is a novel 31kD, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse meteorin is synthesized as a 291 amino… More details

$1015 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Meteorin (METRN), Monoclonal Antibody
Full Product Name
Meteorin
Product Gene Name
Product Synonym Names
Anti -Meteorin
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
7H112
Host
Rat
Species Reactivity
Mouse
Form/Format
Supplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with 200ul sterile 40-50% glycerol, dH2O PBS.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes mouse Meteorin.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, PBS and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
31,207 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (765173..767480). Location: 16p13.3
OMIM
610998
3D Structure
ModBase 3D Structure for Q9UJH8
Immunogen
Recombinant mouse Meteorin.
Hybridoma
Mouse myeloma cells were fused with B cells obtained from a rat immunized with purified, NS0-derived, recombinant mouse Meteorin.

Product Categories/Family for anti-METRN antibody

Applications Tested/Suitable for anti-METRN antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-METRN antibody
Suitable for use in Western Blot and Direct ELISA.
Dilution: Western Blot: 1-2ug/ml. The detection limit is ~5 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold.
Direct ELISA: 0.5-1ug/ml. The detection limit is ~50 ng/well.
Optimal dilutions should be determined by each laboratory for each application.

Other Notes

Small volumes of anti-METRN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METRN purchase

MBS603999 is an antibody targeting METRN. Also known as Meteorin. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for METRN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
meteorin
NCBI Official Synonym Full Names
meteorin, glial cell differentiation regulator
NCBI Official Symbol
METRN
NCBI Official Synonym Symbols
MGC2601; C16orf23; c380A1.2
UniProt Protein Name
Meteorin
Protein Family
UniProt Gene Name
METRN
UniProt Synonym Gene Names
C16orf23
UniProt Entry Name
METRN_HUMAN
NCBI Protein Information
meteorin; OTTHUMP00000045518

NCBI Summary for METRN

Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 [PubMed 15085178]).[supplied by OMIM]

UniProt Comments for METRN

METRN: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Belongs to the meteorin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space

Biological Process: glial cell differentiation; positive regulation of axonogenesis
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000