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Sex Comb on Midleg-Like 2 (SCML2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS604080

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). More details

$610 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sex Comb on Midleg-Like 2 (SCML2), Monoclonal Antibody
Full Product Name
Sex Comb on Midleg-Like 2 (SCML2)
Product Gene Name
Product Synonym Names
Anti -Sex Comb on Midleg-Like 2 (SCML2)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C299
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide, before the addition of glycerol to 40%.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Sex Comb on Midleg-Like 2 at ~77kD. Species Crossreactivity: mouse and rat
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
77,257 Da
Chromosome Location
Chromosome: X; NC_000023.10 (18257433..18372844, complement). Location: Xp22
OMIM
300208
3D Structure
ModBase 3D Structure for Q9UQR0
Immunogen
Partial sequence of recombinant full-length protein to human Sex Comb on Midleg-Like 2

Product Categories/Family for anti-SCML2 antibody

Applications Tested/Suitable for anti-SCML2 antibody
Western Blot (WB), Gel Shift Assay (GS/EMSA)
Application Notes for anti-SCML2 antibody
Suitable for use in Western Blot amd Dot Blot.
Dilution: Western Blot: 0.2-2ug/ml

Testing Data of anti-SCML2 antibody

Mouse Anti-SCML2 Monoclonal Antibody – Cat# MBS604080

Western Blot (WB) of anti-SCML2 antibody

Detection of SCML2 by Western blot. Samples: Whole cell lysate from human HeLa (H, 25ug) , mouse NIH3T3 (M, 25ug) and rat F2408 (R, 25ug) cells. Probed with MBS604080.
Mouse Anti-SCML2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS604080

Other Notes

Small volumes of anti-SCML2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCML2 purchase

MBS604080 is an antibody targeting SCML2. Also known as Sex Comb on Midleg-Like 2 (SCML2). Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SCML2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sex comb on midleg-like protein 2
NCBI Official Synonym Full Names
sex comb on midleg-like 2 (Drosophila)
NCBI Official Symbol
SCML2
NCBI Official Synonym Symbols
SCML2
UniProt Protein Name
Sex comb on midleg-like protein 2
UniProt Gene Name
SCML2
UniProt Entry Name
SCML2_HUMAN
NCBI Protein Information
sex comb on midleg-like protein 2; OTTHUMP00000023000

NCBI Summary for SCML2

This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq]
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UniProt Comments for SCML2

SCML2: a protein of unknown function. Contains a SAM (sterile alpha motif) and two MBT domains.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: PcG protein complex; nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SCML2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with SCML2 and Neoplasms
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