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LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met hyl]-1H-indole-2,3-dione 3-(O-acetyloxime))

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6046140

Cell-permeable. LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1 (Ki = 0.4uM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic… More details

$400 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LDN 57444, UCH-L1 Inhibitor, Biochemical
Full Product Name
LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met hyl]-1H-indole-2,3-dione 3-(O-acetyloxime))
Product Synonym Names
LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met hyl]-1H-indole-2,3-dione 3-(O-acetyloxime))
Sequence
3-(O-acety loxime), 5-chloro-1 -[(2,5-dic hloropheny l)methyl]- 1H-Indole- 2,3-dione
Form/Format
Supplied as a yellow solid.
Purity/Purification
Highly Purified
~98% (TLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
397.64
CAS Number
668467-91-2
Molecular Formula
C17H11Cl3N2O3
Solubility
DMSO (~20mg/ml)

Product Categories/Family for LDN 57444, UCH-L1 Inhibitor biochemical

Biochemicals; Biochem-Inhibitors

Testing Data of LDN 57444, UCH-L1 Inhibitor biochemical

LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met hyl]-1H-indole-2,3-dione 3-(O-acetyloxime)) Biochemical – Cat# MBS6046140

Other Notes

Small volumes of LDN 57444, UCH-L1 Inhibitor biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LDN 57444, UCH-L1 Inhibitor purchase

MBS6046140 is a biochemical targeting LDN 57444, UCH-L1 Inhibitor. Also known as LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met hyl]-1H-indole-2,3-dione 3-(O-acetyloxime)).
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